FV7. Tract of interest-based DTI analysis in upper and lower motor neuron disease variants of ALS

It is still a topic of research if specific clinical presentations of motoneuron disease (MND) patients should be classified as amyotrophic lateral sclerosis (ALS) variants, i.e. primary lateral sclerosis (PLS) with predominant upper motor neuron on the one hand and pure lower motor neuron disease (LMND) on the other hand. Objective markers for ALS are to be investigated in these patients.

Source: Clinical Neurophysiology - July 10, 2018 Category: Neuroscience Authors: H.P. M üller, J. Rosskopf, M. Gorges, F. Agosta, M. Filippi, J. Dorst, A.C. Ludolph, J. Kassubek Source Type: research