Israeli firm gets U.S. nod for advanced trials for non-opiate painkiller

Israeli pharmaceuticals company PainReform has received approval from the U.S. Food and Drug Administration (FDA) to begin late-stage clinical studies for a pain relief drug that is a departure from opiate-based narcotics, it said on Tuesday.
Source: Reuters: Health - Category: Consumer Health News Tags: healthNews Source Type: news

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"I almost died because I didn't call it chest pain," one woman tweeted after surviving a heart attack
Source: Health News: - Category: Consumer Health News Source Type: news
Conclusion: the social representations of health professionals about terminally ill children and adolescents are associated with the situations being experienced, the strategies developed to deal with these moments in the exercise of the profession, and the consequences that this experience causes in the health professionals.RESUMO Objetivo: compreender as representa ções sociais dos profissionais de saúde sobre a terminalidade infantojuvenil. Métodos: trata-se de um estudo de abordagem qualitativa, do tipo exploratório descritivo, realizado com 10 profissionais de saúde, seleciona...
Source: Revista CEFAC - Category: Speech-Language Pathology Source Type: research
This study aimed to explore the role of VPL in the development of OIH and the effect of EA treatment on OIH in rats. RF was administered to rats via the tail vein for OIH induction. Paw withdrawal threshold (PWT) in response to mechanical stimuli and paw withdrawal latency (PWL) to thermal stimulation were tested in rats for the assessment of mechanical allodynia and thermal hyperalgesia, respectively. Spontaneous neuronal activity and local field potential (LFP) in VPL were recorded in freely moving rats using the in vivo multichannel recording technique. EA at 2 Hz frequency (pulse width 0.6 ms, 1-3 ...
Source: Neural Plasticity - Category: Neurology Authors: Tags: Neural Plast Source Type: research
CONCLUSIONS: Data obtained from three colleges was systematically verified, validated and evaluated and a design for an ergonomic student desk was the result. The adoption of these systematic processes gives the design practical validity, and once the ergonomic student desk has completed the manufacturing process, it is expected that its use will lead to a reduction in the incidence of musculoskeletal disorders, neck problems, back pain and pressure on the hips. Ultimately, students having acquired a desk designed to fit their requirements will achieve comfort and satisfaction. PMID: 30526447 [PubMed - as supplied by publisher]
Source: International Journal of Occupational Safety and Ergonomics - Category: Occupational Health Tags: Int J Occup Saf Ergon Source Type: research
ABSTRACT Objective: To evaluate the effect of intravesical hyaluronic acid (HA) treatment on inflammatory cells and the severity of inflammation in an interstitial cystitis rat model created with hydrogen chloride (HCL) via immunohistochemical studies and myeloperoxidase activity for the first time in the literature. Materials and Methods: A total of 30 adult female white Rattus Norvegicus rats were divided into 3 groups as the HCL group, hyaluronic acid treatment (HCL-HA) group and control group. Chemical cystitis was created by administering HCL(400 microL,10 mM) except control group. A single dose of intravesical HA(0.5...
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusion: GoPro® camera proved to be a very interesting tool to document surgerie s without interfering with the procedure and with great educational potential. More studies should be conducted to evaluate the role of this equipment.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusions: Robotic-assisted nephropexy is feasible and can be an excellent minimally invasive alternative technique for the proposed surgery. We reported a shorter hospital stay and a faster postoperative recovery compared with the opened procedure.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusions: Laparoscopic pyeloplasty and concomitant flexible renoscopy through lowermost trocar with basket extraction is a simple, attractive alternative for the simultaneous treatment of ureteropelvic junction obstruction presenting with coexisting nephrolithiasis. This method is useful and feasible, with minimal invasiveness and an early post-operative recovery.
Source: International Braz J Urol - Category: Urology & Nephrology Source Type: research
Conclusion: the results present the need for healthcare professionals to establish action strategies that improve their interaction with the child and their relatives, since an effective interaction makes the process of assessment and management of pain easier, as well as it favors the continuity and the quality of the care provided.
Source: Texto e Contexto - Enfermagem - Category: International Medicine & Public Health Source Type: research
Resumo A s índrome de Lemierre caracteriza-se pela tromboflebite séptica da veia jugular interna, após uma orofaringite, com embolização séptica para o pulmão ou outros órgãos. Neste relato de caso, apresentamos uma paciente feminina, 37 anos de idade, com história de edema e dor em hemiface direita há três dias, associada a fadiga e dispneia progressiva há um dia. História de extração dentária do elemento 48 há três dias. No exame físico admissional, apresentava-se taquipneica, saturand...
Source: Jornal Vascular Brasileiro - Category: Surgery Source Type: research
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