Sleep Apnea Linked to Changes in the Brain in Older Adults

MONDAY, July 9, 2018 -- Obstructive sleep apnea (OSA) is associated with changes to the structure of the brain that are seen in the early stages of dementia, according to a study published online July 5 in the European Respiratory Journal. Nathan E....
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news

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The risk continues beyond the first years that obstructive sleep apnea is diagnosed Related items fromOnMedica Obstructive sleep apnoea Sleep apnoea might increase risk of atrial fibrillation Sleep apnoea in expectant mothers presents risk to newborns Could supplemental oxygen help sleep apnoea patients? Sleep disorder linked to brain changes indicative of dementia
Source: OnMedica Latest News - Category: UK Health Source Type: news
We present how new discoveries from animal models, human sleep experiments, and Alzheimer's disease biomarkers point to an active role of disturbed sleep in dementia pathogenesis. We show preliminary data on how sex, genetics, physical exercise and cognitive reserve can strengthen or weaken the association between obstructive sleep apnea and dementia. We present preliminary results of obstructive sleep apnea treatment, which can slow, stop or reverse neurodegenerative processes accentuated by obstructive sleep apnea, even in individuals already affected by a neurodegenerative disease. We propose future research directions ...
Source: American Journal of Respiratory and Critical Care Medicine - Category: Respiratory Medicine Authors: Tags: Am J Respir Crit Care Med Source Type: research
Epidemiologic and mechanistic evidence is increasingly supporting the notion that obstructive sleep apnea is a risk factor for dementia. Hence, the identification of patients at risk of cognitive decline due to obstructive sleep apnea may significantly improve preventive strategies and treatment decision-making. Cerebrospinal fluid and blood biomarkers obtained through genomic, proteomic and metabolomic approaches are improving the ability to predict incident dementia. Therefore, fluid biomarkers have the potential to predict vulnerability to neurodegeneration in individuals with obstructive sleep apnea, as well as deepen ...
Source: Sleep Medicine Reviews - Category: Sleep Medicine Authors: Tags: Clinical Review Source Type: research
A new study finds that obstructive sleep apnea is tied to brain structure alterations found in early dementia and that low blood oxygen might be a factor.
Source: Health News from Medical News Today - Category: Consumer Health News Tags: Alzheimer's / Dementia Source Type: news
(European Lung Foundation) Obstructive sleep apnea is associated with changes to the structure of the brain that are also seen in the early stages of dementia, according to a study published in the European Respiratory Journal.
Source: EurekAlert! - Medicine and Health - Category: International Medicine & Public Health Source Type: news
CONCLUSION: Multimorbidity is associated with preclinical AD imaging markers of neurodegeneration, but not with amyloid. PMID: 29953971 [PubMed - as supplied by publisher]
Source: Dementia and Geriatric Cognitive Disorders - Category: Psychiatry Tags: Dement Geriatr Cogn Disord Source Type: research
Conclusion: Multimorbidity is associated with preclinical AD imaging markers of neurodegeneration, but not with amyloid.Dement Geriatr Cogn Disord 2018;45:272 –281
Source: Dementia and Geriatric Cognitive Disorders - Category: Geriatrics Source Type: research
Conclusions: A brief educational pamphlet written using health literacy concepts was considered valuable and improved patient knowledge and intention to discuss OSA screening with a physician. Further work is needed to determine whether the pamphlet can promote a discussion and referral for OSA screening at the primary care level.
Source: Journal of Neuroscience Nursing - Category: Neuroscience Tags: Article Source Type: research
Purpose of review Research interest in sleep as a risk factor for dementia has grown, warranting an update in advances over the last 18 months, particularly in the mild cognitive impairment (MCI) stage in which interventions may be best targeted. Recent findings The current systematic review includes empiric research articles published since 2016 that have investigated sleep (excluding obstructive sleep apnea) in MCI. Published articles include case–control studies, those examining clinical correlates of sleep problems, sleep microarchitecture, neuroimaging studies and novel cerebrospinal and blood-based markers...
Source: Current Opinion in Psychiatry - Category: Psychiatry Tags: NEUROCOGNITIVE DISORDERS: Edited by Perminder S. Sachdev Source Type: research
Introduction: Obstructive Sleep Apnea Syndrome (OSA) appears to be involved in the cognitive decline. Atrial fibrillation (AF) may produce multiple cerebral ischemic areas due to microembolic phenomena and transient hypoperfusion, eventually leading to a progressive cognitive impairment and even to acclaimed vascular dementia. In the same time, OSA is common among patients with atrial fibrillation.
Source: Sleep Medicine - Category: Sleep Medicine Authors: Tags: Sleep Breathing Disorders Source Type: research
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