Differential cytotoxic properties of drugs used for intra-articular injection on human chondrocytes: An experimental in-vitro study

CONCLUSIONMorphine and dexamethasone showed no cytotoxic effects in our study and might thus be better alternatives to the clinically frequently applied bupivacaine. S-ketamine induced an intensive dose-dependent cytotoxic effect and should probably be avoided for intra-articular injection.
Source: European Journal of Anaesthesiology - Category: Anesthesiology Tags: Locoregional anaesthesia Source Type: research