GSE116307 Combined systemic disruption of MET and EGFR signaling causes liver failure in normal mice

Conclusion: The present study demonstrates that in addition to controlling the regenerative response, MET and EGFR synergistically control baseline liver homeostasis in normal mice in such a way that their combined disruption leads to liver failure and death.We used microarrays to detail the global programme of gene expression in Delta MET + EGFRi mice liver vs control mice liver
Source: GEO: Gene Expression Omnibus - Category: Genetics & Stem Cells Tags: Expression profiling by array Mus musculus Source Type: research