Multisite Pacing: Have We Reached the Tipping Point of Managing Cardiac Resynchronization Therapy Non-Responders?

Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research

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AbstractAimsDiabetes mellitus (DM) has a negative impact on prognosis in patients with heart failure (HF). The role impact of DM in HF patients with implantable cardioverter defibrillator (ICD) or cardiac resynchronization therapy (CRT) devices might differ and remains unclear. The aim of our study was to investigate the impact of DM on periprocedural complications and clinical outcome in HF patients undergoing ICD or CRT implantation.Methods and resultsWithin the German Device Registry, data from 50 German centres were collected between January 2007 and February 2014. A retrospective analysis ofn = 5329 patients undergoin...
Source: ESC Heart Failure - Category: Cardiology Authors: Tags: Original Research Article Source Type: research
Heightened sympathetic nerve activity has been associated with poorer prognosis in patients with reduced left ventricular systolic function (HFrEF).
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research
Cardiac resynchronization therapy (CRT) reduces the risk of mortality and heart failure events in select patients with left ventricular systolic dysfunction.1 –4 Prior studies have suggested underuse of CRT among eligible patients.5 Within a large regional health care system, we sought to identify and address potential underuse of CRT.
Source: Journal of Cardiac Failure - Category: Cardiology Authors: Tags: Research Letter Source Type: research
Abbott won clearance in the European Union for its new Gallant implantable cardioverter defibrillator (ICD) and cardiac resynchronization therapy defibrillator (CRT-D) implants. The MRI compatible devices, which Abbott claims have an extended bat...
Source: Medgadget - Category: Medical Devices Authors: Tags: Cardiac Surgery Cardiology Source Type: blogs
Publication date: Available online 21 February 2020Source: American Heart JournalAuthor(s): Marat Fudim, Frederik Dalgaard, Sana M. Al-Khatib, Daniel Friedman, Kathryn Lallinger, William T. Abraham, John G.F. Cleland, Anne B. Curtis, Michael R. Gold, Valentina Kutyifa, Cecilia Linde, Daniel E. Schaber, Anthony Tang, Fatima Ali-Ahmed, Sarah Goldstein, Brystana Kaufman, Robyn Fortman, J. Kelly Davis, Lurdes Y.T. Inoue, Gillian D. SandersAbstractBackgroundAlthough cardiac resynchronization therapy (CRT) is effective for some patients with heart failure and a reduced left ventricular ejection fraction (HFrEF), evidence gaps re...
Source: American Heart Journal - Category: Cardiology Source Type: research
ConclusionFemales were associated with persistently reduced odds of receipt of CRT-D compared to males over an eleven-year period. The present study identifies important factors that predict the choice of CRT device offered to patients in the US.
Source: Canadian Journal of Cardiology - Category: Cardiology Source Type: research
AbstractBackgroundLimited studies are available on the clinical significance of left ventricular lead polarity in patients undergoing cardiac resynchronization (CRT), with a recent study suggesting better outcomes with LV true bipolar pacing.ObjectivesWe aimed to determine whether True ‐Bipolar LV pacing is associated with reduced mortality in a large, real‐life CRT cohort, followed by remote monitoring.MethodsWe analyzed de ‐identified device data from CRT patients followed by the Boston Scientific LATITUDE remote monitoring database system. Patients with LV bipolar leads paced between the LV ring and LV tip were id...
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: ELECTROPHYSIOLOGY Source Type: research
Conclusions: This retrospective registry-based study provides a picture of CIED first implants in HCM patients in a Swedish tertiary university hospital. ICDs were the most commonly implanted devices, covering 59% of CIED implants. HCM patients receiving a pacemaker or an ICD had different epidemiological and clinical profiles. PMID: 32054352 [PubMed - as supplied by publisher]
Source: Scandinavian Cardiovascular Journal - Category: Cardiology Tags: Scand Cardiovasc J Source Type: research
ConclusionsInadequate programming (active LV sensing with T ‐wave protection) is the main cause of impaired resynchronization in devices with left ventricular sensing. In general, we recommend the deactivation of the LV T‐wave protection function.This article is protected by copyright. All rights reserved
Source: Pacing and Clinical Electrophysiology : PACE - Category: Cardiology Authors: Tags: DEVICES Source Type: research
CONCLUSIONS: Among HF patients with LVEF ≤ 35%, clinical factors including older age, CAD, and previous MI are associated with transmural LGE in the posterolateral wall, while CAD is associated with LGE. This data may have potential implications for planning ICD and CRT placement procedures. PMID: 32037500 [PubMed - as supplied by publisher]
Source: Cardiology Journal - Category: Cardiology Authors: Tags: Cardiol J Source Type: research
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