Optic nerve oedema at high altitude occurs independent of acute mountain sickness.

Optic nerve oedema at high altitude occurs independent of acute mountain sickness. Br J Ophthalmol. 2018 Jul 04;: Authors: Schatz A, Guggenberger V, Fischer MD, Schommer K, Bartz-Schmidt KU, Gekeler F, Willmann G Abstract BACKGROUND/AIMS: The study aims to investigate changes in the optic nerve sheath diameter (ONSD) at high altitude and to assess correlation to optic disc oedema (ODE) and acute mountain sickness (AMS). This investigation is part of the Tübingen High Altitude Ophthalmology study. METHODS: Fourteen volunteers ascended to 4559 m for 4 days before returning to low altitude. Ultrasonography of ONSD, quantification of optic disc parameters using a scanning laser ophthalmoscope and fluorescein angiography were performed at 341 m and at high altitude. Pearson's coefficient was used to correlate changes in ONSD with the optic disc and AMS. Assessment of AMS was performed using the Lake Louise (LL) and AMS-cerebral (AMS-C) scores of the Environmental Symptom Questionnaire-III. All volunteers were clinically monitored for heart rate (HR) and oxygen saturation (SpO2). RESULTS: The mean ONSD at high altitude (4.6±0.3 mm, p
Source: The British Journal of Ophthalmology - Category: Opthalmology Authors: Tags: Br J Ophthalmol Source Type: research

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