Osteopontin induces ductular reaction contributing to liver fibrosis

Conclusions
OPN emerges as a key matricellular protein driving DR and contributing to scarring and liver fibrosis via TGF-β.

Source: Gut - October 2, 2014 Category: Gastroenterology Authors: Wang, X., Lopategi, A., Ge, X., Lu, Y., Kitamura, N., Urtasun, R., Leung, T.-M., Fiel, M. I., Nieto, N. Tags: Cirrhosis, Pancreas and biliary tract Hepatology Source Type: research