CCL20 mediates lipopolysaccharide induced liver injury and is a potential driver of inflammation and fibrosis in alcoholic hepatitis

Conclusions
Our results suggest that CCL20 upregulation is strongly associated with LPS and may not only represent a new potential biomarker to predict outcome in patients with AH but also an important mediator linking hepatic inflammation, injury and fibrosis in AH.

Source: Gut - October 2, 2014 Category: Gastroenterology Authors: Affo, S., Morales-Ibanez, O., Rodrigo-Torres, D., Altamirano, J., Blaya, D., Dapito, D. H., Millan, C., Coll, M., Caviglia, J. M., Arroyo, V., Caballeria, J., Schwabe, R. F., Gines, P., Bataller, R., Sancho-Bru, P. Tags: Hepatitis other Hepatology Source Type: research