Postinduction serum infliximab trough level and decrease of C-reactive protein level are associated with durable sustained response to infliximab: a retrospective analysis of the ACCENT I trial

Conclusions
Patients with durable sustained response to maintenance infliximab 5 mg/kg had higher postinduction trough levels than patients without durable sustained response. Serum infliximab trough levels ≥3.5 µg/mL and ≥60% CRP decrease were significantly associated with durable sustained response.

Source: Gut - October 2, 2014 Category: Gastroenterology Authors: Cornillie, F., Hanauer, S. B., Diamond, R. H., Wang, J., Tang, K. L., Xu, Z., Rutgeerts, P., Vermeire, S. Tags: Crohn's disease, Open access Inflammatory bowel disease Source Type: research