Neuroinflammatory responses in experimental and human stroke lesions

Neuroinflammation has been suggested as an attractive treatment target in stroke, since it offers a broader therapeutic window in comparison to currently established thrombolytic approaches. Inflammatory cells of both the innate and the adaptive immune system have been identified in experimental as well as human stroke lesions. In animal models, various therapeutic strategies targeting neuroinflammation have shown beneficial effects, however, translation to human disease has so far been disappointing.
Source: Journal of Neuroimmunology - Category: Allergy & Immunology Authors: Tags: Review Source Type: research