Antagonistic metabolites produced by the fungus Curvularia sp. BCC52426 against Aspergillus sp. BCC51998

Publication date: August 2018Source: Phytochemistry Letters, Volume 26Author(s): Nantiya Bunbamrung, Chakapong Intaraudom, Aibrohim Dramae, Nattawut Boonyuen, Rungtiwa Chanthaket, Pranee Rachtawee, Pattama PittayakhajonwutAbstractFour previously undescribed compounds, including (Z)-chloromonilinic acid B (1), (E)-chloromonilinic acid C (2), 4-chlorocurvularin (5), and 4-chlorocurvularinic acid (6), together with four known compounds, (E)-chloromonilinic acids A and B, pinselin, and anhydromevalonolactone, were isolated from the fungus Curvularia sp. BCC52426. The chemical structures were determined by comparing their NMR spectra to documented spectra of the related compounds and the isolated compounds were also appraised for antimicrobial activity and cytotoxicity.Graphical abstract

Source: Phytochemistry Letters - July 6, 2018 Category: Chemistry Source Type: research