Expression analysis of extracellular microRNA in bronchoalveolar lavage fluid from patients with pulmonary sarcoidosis

Respirology, EarlyView.
Source: Respirology - Category: Respiratory Medicine Authors: Source Type: research

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This study aimed to determine the frequency and pattern of different granulomatous skin lesions in the Dermatopathology Department of Hospital de Santa Maria (Lisboa, Portugal). A retrospective study of all skin biopsies with granulomatous lesions received during a period of 10 years (2008–2017) was performed. Clinical and histopathological characteristics of the selected cases were analyzed, and the lesions were categorized according to histological type of granuloma and etiology. Foreign-body granulomas secondary to ruptured cyst, folliculitis, or suture material were excluded. From a total of 48,253 cutaneous biop...
Source: The American Journal of Dermatopathology - Category: Pathology Tags: CME Article Source Type: research
No abstract available
Source: The American Journal of Dermatopathology - Category: Pathology Tags: Letters to the Editor Source Type: research
Conclusions: Orbital sarcoidosis is seen in a high TB endemic country like India and is definitely underreported. PMID: 32073939 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
We describe three cases of lymphoma in which lymphoma mimicked other diseases causing neurological dysfunction, specifically sarcoidosis, vasculitis and infection respectively. Case 1 was a 66-year-old man with subacute progressive diplopia and gait disturbance and investigations revealing a supratentorial para-falcine soft tissue lesion, mid-thoracic cord enhancement and right axillary mass and an elevated serum ACE. Right axillary mass core biopsy was diagnostic of Burkitt lymphoma. Case 2 was a 50-year-old man with several weeks of constitutional symptoms and development of lower limb weakness and numbness, urinary rete...
Source: Journal of Clinical Neuroscience - Category: Neuroscience Source Type: research
Conclusion: Etiologies of uveitis have changed over the years. Further development of novel tests and diagnostic criteria would increase definitive diagnosis for unclassified uveitis. (147/150 words). PMID: 32068467 [PubMed - as supplied by publisher]
Source: Ocular Immunology and Inflammation - Category: Allergy & Immunology Tags: Ocul Immunol Inflamm Source Type: research
ConclusionsICD placement in CS is associated with high incidence of both appropriate and inappropriate therapy. High degree AV block appears to be predictive of appropriate ICD therapy.
Source: Journal of Interventional Cardiac Electrophysiology - Category: Cardiology Source Type: research
ConclusionsIn this study, high serum adiponectin level was detected in patients with sarcoidosis while serum leptin level was similar in the sarcoidosis and control group. Adiponectin, an anti-inflammatory protein, may play a role in the pathogenesis of sarcoidosis. Studies are needed to shed light on this topic.Key Points• Sarcoidosis is a chronic granulomatous disease characterized by granuloma formation• High serum adiponectin level was found in sarcoidosis patients• Serum adiponectin level was associated with some clinical features such as arthralgia and arthritis• High adiponectin levels in sarcoid...
Source: Clinical Rheumatology - Category: Rheumatology Source Type: research
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
Source: Journal of Nuclear Cardiology - Category: Nuclear Medicine Source Type: research
We have read with great interest the study by Huitema et al. [1] showing a pulmonary hypertension (PH) prevalence of around 3% in a large cohort of predominantly Caucasian sarcoidosis patients in a Dutch tertiary centre. According to the authors, a European Caucasian cohort has never been studied before this PULmonary hypertension in pulmonary SARcoidosis (PULSAR) study. In this context, in 2013 we reported another PULSAR study (PULmonary hypertension in SARcoidosis) in an albeit smaller cohort from a German tertiary centre [2]. Of interest, we showed very similar results, with a prevalence of precapillary PH of 3.6% with ...
Source: European Respiratory Journal - Category: Respiratory Medicine Authors: Tags: Original Articles: Correspondence Source Type: research
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