Butter Increases High-Density Lipoprotein Functional Capacity: Is This Compensation for Its Adverse Effect on Serum Low-Density Lipoprotein Cholesterol?

Controversy over the dietary guidelines to reduce SFA intake rests heavily on the lack of evidence for a direct association between dietary SFAs and lower cardiovascular disease (CVD) mortality (1,2). Evidence that a lower intake of SFAs reduces CVD events has been reported, and can be explained, in part, by the lowering of serum LDL cholesterol (2), a causal risk factor for the development of CVD (3). Somewhat counterintuitively, the effects of SFAs on the putatively beneficial serum HDL cholesterol run in parallel to that of LDL cholesterol, but how these diet-induced changes in HDL cholesterol impact on CVD risk is less clear.

Source: Journal of Nutrition - June 13, 2018 Category: Nutrition Source Type: research