A randomized controlled trial of a Supportive Expressive Group intervention for Women with a Family History of breast Cancer

Psycho-Oncology,Volume 0, Issue ja, -Not available-.
Source: Psycho-Oncology - Category: Cancer & Oncology Authors: Source Type: research

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This study demonstrated that using the dual-energy method could improve classification performance because the microcalcifications are affected by the density and thickness of the breast phantom. These results indicate that the classification accuracy was improved when the difference between the low-energy image and high-energy image was used. The dual-energy method can reduce the frequency of the need for biopsies and discriminate between different types of microcalcifications in mammography. These results can improve the efficiency of early breast cancer diagnosis.
Source: Radiation Physics and Chemistry - Category: Physics Source Type: research
Publication date: Available online 19 April 2019Source: Life SciencesAuthor(s): Jiaxin Zuo, Yameng Jiang, Enxia Zhang, Yuling Chen, Ze Liang, Jie Zhu, Yinan Zhao, Hong Xu, Guoliang Liu, Jiasi Liu, Wei Wang, Shubiao Zhang, Yuhong ZhenAbstractAimsTo investigate the antitumor effect of 7-O-geranylquercetin (GQ) combining with survivin siRNA (siSuvi) or IL-10 siRNA (siIL-10) to breast cancer.Main methodsXenograft tumor model was established by subcutaneously inoculating human breast cancer MCF-7 cells in BALB/c nude mice. Transfection efficiency of siRNA mediated by cationic liposome CDO14 in MCF-7 cells and tumor bearing mice...
Source: Life Sciences - Category: Biology Source Type: research
Publication date: 1 July 2019Source: Colloids and Surfaces B: Biointerfaces, Volume 179Author(s): Mania Habibi Jouybari, Seyedehgolshan Hosseini, Khadijeh Mahboobnia, Lily Azadeh Boloursaz, Mostafa Moradi, Mohammad IraniAbstractIn the present study, the tri-layer nanofibers were synthesized via triaxial electrospinning process to control the sustained delivery of Doxorubicin (DOX), Paclitaxel (PTX) and 5- fluorouracil (5-FU) anticancer drugs from nanofibers. The 5-FU molecules were incorporated into the core solution (chitosan/polyvinyl alcohol (CS/PVA)) to fabricate the CS/PVA/5-FU inner layer of nanofibers. The intermedi...
Source: Colloids and Surfaces B: Biointerfaces - Category: Biochemistry Source Type: research
Millions of people have bought into the mail-in DNA testing craze, but a new study indicates consumers should be aware of the limitations of the health tests offered.   Those who expect 23andMe to detect most breast cancer risks are being cautioned after study findings determined almost 90 percent of participants with a BRCA mutation wouldn’t have received a positive from the company’s test, reports The New York Times. The test’s limited scope is to bla me, per The Daily Beast. The study,…
Source: bizjournals.com Health Care:Biotechnology headlines - Category: Biotechnology Authors: Source Type: news
Condition:   Triple Negative Breast Cancer Intervention:   Sponsor:   European Institute of Oncology Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   HR+/HER2- Locally Advanced, Metastatic Breast Cancer Intervention:   Drug: Palbociclib Sponsor:   Pfizer Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: July 2019Source: Phytochemistry, Volume 163Author(s): Leila Gimenes, Joao Marcos Batista Junior, Fernando Martins dos Santos Junior, Matheus da Silva Souza, Liany Luna-Dulcey, Javier Esteves Ellena, Marcia Regina Cominetti, Maria Fatima das Graças Fernandes da Silva, Paulo Cezar Vieira, Joao Batista Fernandes, Dan StaerkAbstractTwo highly oxygenated nortriterpenes, picraviane A and B, were isolated from the ethanolic extract of Picramnia glazioviana Engl. The structures were determined by analysis of HRMS and 2D NMR spectroscopic data. Single-crystal X-ray diffraction data was also obtained for pic...
Source: Phytochemistry - Category: Chemistry Source Type: research
Lab testing for the genes that predispose a person to develop cancer is highly complex, both to preform and interpret. For example and relating to BRCA, I have blogged about some of the pitfalls of such testing (see:BRCA Exchange Available on the Web; Understanding BRCA Variants). Here's a quote from this note discussing some of the complexities that are encountered:It's not known among some healthcare consumers that there are a host of BRCA variants other than the standard ones. Normal BRCA testing looks forthree specific genetic variants that are linked to hereditary cancers. Two of these variants &mdas...
Source: Lab Soft News - Category: Laboratory Medicine Authors: Tags: Clinical Lab Industry News Clinical Lab Testing Diagnostics Direct Access Testing (DAT) Food and Drug Administration Genomic Testing Healthcare Innovations Lab Industry Trends Lab Regulation Medical Consumerism Medical Education Medi Source Type: blogs
Cellular quiescence, a reversible state in which growth, proliferation, and other cellular activities are arrested, is important for self-renewal, differentiation, development, regeneration, and stress resistance. However, the physiological mechanisms underlying cellular quiescence remain largely unknown. In the present study, we used embryos of the crustacean Artemia in the diapause stage, in which these embryos remain quiescent for prolonged periods, as a model to explore the relationship between cell-membrane potential (Vmem) and quiescence. We found that Vmem is hyperpolarized and that the intracellular chloride concen...
Source: Journal of Biological Chemistry - Category: Chemistry Authors: Tags: Cell Biology Source Type: research
Dermatology
Source: Dermatology - Category: Dermatology Source Type: research
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