Assessing Plasmodium falciparum transmission in mosquito-feeding assays using quantitative PCR
Evaluating the efficacy of transmission-blocking interventions relies on mosquito-feeding assays, with transmission typically assessed by microscopic identification of oocysts in mosquito midguts; however, mic...
A gene enabled the malaria parasite to infect both gorillas and humans for a limited time, explaining how the jump was made at a molecular level, researchers say.
Discovery of mutation 50,000 years ago could help in the fight against malaria.
ConclusionAccording to our results, Nested PCR method had higher sensitivity than LM and is suggested as a good approach for malaria detection. Consideration the wide diversity of tested isolates and the importance of vaccine development, which is affected by this diversity, further studies are needed in this regard.
Scientists who resurrected a 50,000-year-old gene sequence have analyzed it to figure out how the world's deadliest malaria parasite jumped from gorillas to humans - giving insight into the origins of one of human history's biggest killers.
Environmental destruction risks increasing the spread of deadly diseases including Ebola and malaria, with serious consequences for future public health
[Radio Dabanga] Khartoum / Kassala / El Fasher -The Sudanese Health Ministry announced a plan to contain the spread of vector-borne diseases in seven states in eastern and western Sudan. In North Darfur, 12 cases of acute haemorrhagic fever and more than 49,000 new cases of malaria were recorded during the past four weeks.
Contributors : Wieteke A Hoeijmakers ; Rich árd Bártfai ; Christa G ToenhakeSeries Type : Expression profiling by high throughput sequencingOrganism : Plasmodium falciparumEpigenetic regulatory mechanisms are central to the development and survival of all eukaryotic organisms. These mechanisms critically depend on the marking of chromatin domains with distinctive histone tail modifications (PTMs) and their recognition by effector protein complexes. In this project, histone peptide pull-downs and protein-protein interaction quantitative proteomics were used to unveil interactions between PTMs and associated re...
ACS Chemical BiologyDOI: 10.1021/acschembio.9b00739
Date: Wednesday, 11 13, 2019; Speaker: Lawrence Wang, Doctoral Candidate, Immunology Laboratory, Cellular Immunology Section, National Institute of Allergy and Infectious Diseases, VRC; Building: Building 45 (Natcher Building); Ruth Kirschstein Auditorium
Date: Wednesday, 11 13, 2019; Speaker: Laura Amo, Ph.D. , Postdoctoral Fellow, Laboratory of Immunogenetics, National Institute of Allergy and Infectious Diseases; Building: Building 45 (Natcher Building); Ruth Kirschstein Auditorium