Early-life socioeconomic disadvantage, not current, predicts accelerated epigenetic aging of monocytes

Aging-related chronic diseases such as heart disease, diabetes, and cancer are among the leading causes of death worldwide. Morbidity and mortality from these conditions are disproportionately high among socioeconomically disadvantaged individuals (Braveman& Barclay, 2009). Although much evidence comes from studies of socioeconomic status (SES) during adulthood, accumulating data suggest early-life SES is also associated with age-related health problems. Independent of adulthood SES, early-life SES confers increased risk for upper respiratory infection, premature death, and morbidity and mortality from cardiovascular disease and cancer (reviewed in Miller et al.

Source: Psychoneuroendocrinology - July 5, 2018 Category: Psychiatry Authors: Makeda K. Austin, Edith Chen, Kharah M. Ross, Lisa M. McEwen, Julia L. Maclsaac, Michael S. Kobor, Gregory E. Miller Tags: Short Communication Source Type: research