Striatal cerebral blood flow, executive functioning, and fronto-striatal functional connectivity in clinical high risk for psychosis

Patients at clinical high risk (CHR) for psychosis exhibit increased striatal cerebral blood flow (CBF) during the resting state and impaired cognitive function. However, the relation between CBF and cognitive impairment is unknown. We therefore studied the association between striatal CBF and executive functioning and evaluated the functional connectivity (FC) between dorsal striatum and the frontal cortex in CHR.

Source: Schizophrenia Research - July 5, 2018 Category: Psychiatry Authors: Daniela Hubl, Frauke Schultze-Lutter, Martinus Hauf, Thomas Dierks, Andrea Federspiel, Michael Kaess, Chantal Michel, Benno G. Schimmelmann, Jochen Kindler Source Type: research