Intérêt de l’index de sévérité de la gangrène de Fournier dans la prédiction des facteurs pronostiques de la mortalité

ConclusionL’ISGF calculé à partir des aberrations physiques et métaboliques constitue un outil simple, fiable et valide dans l’évaluation de la gravité initiale de la maladie, et avec une valeur seuil de 9, il permet de prédire la mortalité avec une sensibilité et spécificité élevées.AbstractIntroductionFournier's gangrene severity index (FGSI) is a numeric score calculated from physiological parameters. It is a tool to predict the severity of this disease. The aim of our study is to identify the prognostic factors of mortality risk and to validate the FGSI.Patients and methodsWe reviewed retrospectively medical records of patients admitted for Fournier's gangrene between 2002 and 2012. Statistical analysis were performed by SPSS 10 for Windows software, a significance level was selected for a p <0.05.ResultsSixty patients diagnosed with Fournier's gangrene were collected, seven deaths were observed and mortality rate was 11,66%. The average age of our patients was 57,7 years and they were all male. Based on clinical and biological parameters, we established FGSI for each patient, and the mean FGSI score was significantly increased in patients who died (10.14 ± 2.41) compared to survivors (6.23 ± 3.47) (P = 0.006). Using a FGSI score threshold of 9 (sensitivity 71.4%, specificity 84.9%), we observed that the mortality rate was significantly higher in the group of patients with FGSI score greater than 9 (38.4%) compared to (4.3%) in the group of patients ...
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research