Prise en charge du priapisme ischémique aigu à l’Hôpital National de Lamordé de Niamey

ConclusionLa drépanocytose est la principale cause du priapisme ischémique aigu dans notre contexte. La ponction caverneuse selon Winter est une option thérapeutique simple, fiable et efficace pour la prise en charge de cette affection.AbstractObjectivesTo describe the clinical features of acute ischemic priapism and to assess the results of the management.Patients and methodsThis is a prospective study over a period of 19 months from June 2011 to December 2012, involving 29 patients treated for acute ischemic priapism in the service of surgical and urological emergencies of National hospital of Lamordé. The age, the consultation period, the etiology and results of the treatment were the variables studied.ResultsThe mean age was 19 years (range 5-43 years). The average time of consultation was 26 hours (range: 5 hours and 5 days). Sickle cell disease (18 cases) and self-medication (7 cases) were the main causes. De tumescence was complete (15 cases) after cavernous puncture and etilefrine administration. The erection was satisfactory (7 cases) with a mean of 3 months and 5 patients had erectile dysfunction.ConclusionSickle cell disease is the leading cause of acute ischemic priapism in our context. Winter's procedure is a simple treatment option, reliable and effective for the treatment of this condition.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research

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CONCLUSION: Priapism is a condition that often requires emergency treatment to spare erectile function. It appears crucial to know this condition and its management. PMID: 30201552 [PubMed - as supplied by publisher]
Source: Progres en Urologie - Category: Urology & Nephrology Tags: Prog Urol Source Type: research
ConclusionLa drépanocytose est la principale cause du priapisme ischémique aigu dans notre contexte. La ponction caverneuse selon Winter est une option thérapeutique simple, fiable et efficace pour la prise en charge de cette affection.AbstractObjectivesTo describe the clinical features of acute ischemic priapism and to assess the results of the management.Patients and methodsThis is a prospective study over a period of 19 months from June 2011 to December 2012, involving 29 patients treated for acute ischemic priapism in the service of surgical and urological emergencies of National hospital of Lamord...
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
Ischemic priapism is a sustained erection lasting more than 4 hours, and can lead to permanent penile scarring. It is estimated that between 44-90% of priapic episodes lasting more than 24 hours lead to erectile dysfunction (ED). Individuals with hematological disorders, especially those with sickle-cell anemia, are at higher risk of developing priapism. Using sickle transgenic-knockout Berkeley (BERK) mice as our model for sickle-cell anemia, we compared gene expression patterns in the corpora cavernosa between sickle-cell mice and control mice in order to identify genes of interest for future research.
Source: The Journal of Urology - Category: Urology & Nephrology Authors: Tags: Sexual Function/Dysfunction: Basic Research & Pathophysiology II Source Type: research
​BY KEVAL PATEL, &AHMED RAZIUDDIN, MDA 41-year-old man with a past medical history of bipolar disorder, PTSD, and alcohol abuse presented to the emergency department for an erection that wouldn't go away. He said his erection had persisted for 28 hours and was starting to be painful. He had taken trazodone the day before but was unable to recall the dosage. He denied any erectile dysfunction in the past when he was on trazodone a year before.Physical examination showed an uncomfortable-appearing man lying supine in bed but in no acute distress. The physical exam was normal except for the genitourinary exam, which rev...
Source: The Case Files - Category: Emergency Medicine Tags: Blog Posts Source Type: research
Conclusion : Sickle cell disease is the leading cause of acute ischemic priapism in our context. Winter's procedure is a simple treatment option, reliable and effective for the treatment of this condition.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
Summary In patients with sickle cell anemia, the sickling of red blood cells is known to cause end‐organ damage by infarction. In some men who are affected by sickle cell anemia, the obstruction of venous outflow of the penis causes priapism, which could lead to erectile dysfunction. There is also evidence that the disease is linked to other reproductive issues in men—specifically delayed puberty, low testosterone, and sperm abnormalities—although the causes of these problems are less clear. Treatment of sickle cell anemia can have effects on the reproductive system as well. This review summarizes the finding...
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Review Article Source Type: research
Conclusions: Low flow priapism is common in our environment, and approximately half will occur in SCD patients who have had stuttering priapism previously. Timely diagnosis and treatment will reduce the probability of severe ED. In our experience, the Al-Ghorab shunt provides rapid relief. Enlightenment is vital in reducing ischemia time. Emphasis on preventive measures in SCD patients is vital.
Source: Nigerian Journal of Clinical Practice - Category: Rural Health Authors: Source Type: research
We report case of priapism caused by hyperhomocysteinemia with favorable outcome with only few cases so far reported in the literature to the best of our knowledge. A 31 year-old male referred to our institution with non resolving priaprism for the last 6 days. Immediate distal shunt (Al-ghorab) was created but it could not achieve the detumescence. The penile Doppler showed no flow into the corpora, so a proximal shunt (Quackels) was made which achieved satisfactory detumescence. On thorough evaluation for the cause of priaprism, only homocysteine level was found to be significantly raised (40.46 µmol/L), being the u...
Source: Urology Annals - Category: Urology & Nephrology Authors: Source Type: research
Priapism, a clinical disorder of erection, is associated with physical and psychological harm to patients. Its ischemic form is associated with penile pain and erectile tissue loss, potentially leading to permanent erectile dysfunction (ED). Ischemic priapism is notably common in sickle cell disease patients. Given that recent studies have implicated the nitrergic pathway in its pathophysiology, this randomized, double-blind, placebo-controlled clinical trial investigated the safety and efficacy of a phosphodiesterase type 5 inhibitor, sildenafil, in preventing ischemic priapism in sickle cell disease (SCD) patients.
Source: Urology - Category: Urology & Nephrology Authors: Source Type: research
Priapism is a disorder of persistent penile erection unrelated to sexual interest or desire. This pathologic condition, specifically the ischemic variant, is often associated with devastating complications, notably erectile dysfunction. Because priapism demonstrates high prevalence in patients with hematologic disorders, most commonly sickle cell disease (SCD), there is significant concern for its sequelae in this affected population. Thus, timely diagnosis and management are critical for the prevention or at least reduction of cavernosal tissue ischemia and potential damage consequent to each episode. Current guidelines a...
Source: Blood - Category: Hematology Authors: Tags: How I Treat, Free Research Articles, Vascular Biology Source Type: research
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