The role of 3-dimensional sonography and virtual sonographic cystscopy in detection of bladder tumors

ConclusionAdditional to lower costs and no radiation exposure, 3D sonography appears comparable to the use of CT scans and MRI in providing virtual cystoscopy in investigating bladder cancer. Virtual sonographic cystoscopy may therefore be a useful alternative for screening and follow up of tumors, particularly if conventional cystoscopy cannot be performed. However, 3D sonography cannot replace pathological staging, and there is still a need to further improve this technology for enhanced assessment of mucosal abnormalities.
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research

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Authors: Goto T, Miyamoto H PMID: 32208041 [PubMed - as supplied by publisher]
Source: Expert Review of Anticancer Therapy - Category: Cancer & Oncology Tags: Expert Rev Anticancer Ther Source Type: research
This study thoroughly analyzed E-cadherin and associated changes in BC, and reports Ephrin-B1 as a new marker of tumor aggressiveness.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
In conclusion, our study indicated that CRYAB, CGNL1, ECM1, and GPX3 are potential urine biomarkers of HGBC. These four novel urine biomarkers will have attractive applications to provide new diagnostic methods, prognostic predictors and treatment targets for HGBC, which could improve the prognosis of HGBC patients, if validated by further experiments and larger prospective clinical trials.
Source: Frontiers in Oncology - Category: Cancer & Oncology Source Type: research
For mixed population of patients with non –muscle‐invasive bladder who were treated with and without Bacillus Calmette‐Guerin and without any immediate postoperative chemotherapy, we show that European Organisation for Research and Treatment of Cancer scale provides the best recurrence and progression prediction in comparison with Eur opean Association of Urology and Club Urologico Espanol de Tratamiento Oncologico risk scores. We highlight the role of diameter and tumor extent in transition prediction. AbstractBrief Description: The results demonstrate that the European Organisation for Research and Treatment of...
Source: Cancer Medicine - Category: Cancer & Oncology Authors: Tags: ORIGINAL RESEARCH Source Type: research
Biomarkers of carcinogens with a strong link to bladder cancer are present in urine of e-cigarette users, a systematic review suggests.Reuters Health Information
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Hematology-Oncology News Source Type: news
Condition:   Rectal Cancer Intervention:   Procedure: Empty Bladder planning CT scan and CBCTs Sponsor:   Institut Cancerologie de l'Ouest Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Abstract Interest in nanostructures such as titanate nanotubes (TNT) has grown notably in recent years due to their biocompatibility and economic viability, making them promising for application in the biomedical field. Quercetin (Qc) has shown great potential as a chemopreventive agent and has been widely studied for the treatment of diseases such as bladder cancer. Motivated by the possibilities of developing a new hybrid nanostructure with potential in biomedical applications, this study aimed to investigate the incorporation of quercetin in sodium (NaTNT) and zinc (ZnTNT) titanate nanotubes, and characterize t...
Source: Appl Human Sci - Category: Physiology Authors: Tags: Mater Sci Eng C Mater Biol Appl Source Type: research
In this study, we analyzed the tumor tissues of 224 patients with pTa, pT1, and pT2 urinary bladder cancer. We performed a histomorphologic analysis and immunohistochemistry for p53, Ki-67, and E-cadherin, which were selected as markers of the malignant process. For pTa and pT1, univariate analyses of cancer-specific survival (CSS), progression-free survival (PFS), and recurrence-free survival (RFS) were calculated using the Kaplan-Meier method, the log-rank test and Cox regression. Multivariate analysis was performed by a Cox regression analysis. Ki-67 (P
Source: European Journal of Histochemistry - Category: Biomedical Science Source Type: research
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Source: Radiotherapy and Oncology - Category: Radiology Authors: Tags: Letter to the Editor Source Type: research
Abstract The immune system is important to control tumor development and progression. However, tumor cells and cells of the tumor microenvironment can induce immune escape mechanisms including activation of immune checkpoints such as PD-1/PD-L1. Based on this knowledge, new immune therapies including PD-1 and PD-L1 inhibition have been developed and are already recommended as standard treatment in metastatic bladder and kidney cancer patients. In addition to its role as a therapeutic target PD-L1 seems to be a prognostic parameter although data are controversial. Only little is known about signaling pathways induc...
Source: Current Drug Targets - Category: Drugs & Pharmacology Authors: Tags: Curr Drug Targets Source Type: research
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