Nomogram for predicting the probability of the positive outcome of prostate biopsies among Ghanaian men

Publication date: March 2018Source: African Journal of Urology, Volume 24, Issue 1Author(s): F.A. Yeboah, E. Acheampong, C.K. Gyasi-Sarpong, K. Aboah, E.F. Laing, C. Obirikorang, B.T. Frimpong, G. Amoah, E.N. Batu, E.O. Anto, B. AmankwaahAbstractIntroduction and objectivesSeveral existing models have been developed to predict positive prostate biopsy among men undergoing evaluation for prostate cancer (PCa). However, most of these models have come from industrialized countries. We therefore, developed a prostate disease nomogram model to provide a basis for predicting a prostate biopsy outcome by correlating clinical indicators and diagnostic parameters among Ghanaian men.Subjects and methodsThe study was a hospital-based cross-sectional prospective one which was undertaken at the Department of Surgery (Urology Unit) Komfo Anokye Teaching Hospital (KATH) from December, 2014 to March, 2016. In all a total of 241 patients suspected of having a prostate disorder due based on an abnormal digital rectal examination (DRE) findings and, or elevated prostate specific antigen (PSA) level underwent Trans-Rectal Ultrasonography (TRUS) guided biopsy of the prostate. Stepwise logistic regression was used to determine the independent predictors of a positive initial biopsy. Age, prostate-specific antigen (PSA), digital rectal examination (DRE) status, prostate specific antigen density (PSAD), history of alcohol consumption and history of smoking findings were included in the analysis. Two ...
Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research

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Source: African Journal of Urology - Category: Urology & Nephrology Source Type: research
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