Mediation analysis to understand genetic relationships between habitual coffee intake and gout

Increased coffee intake is associated with reduced serum urate concentrations and lower risk of gout. Specific alleles of the GCKR, ABCG2, MLXIPL, and CYP1A2 genes have been associated with both reduced coffee in...

Source: Arthritis Research and Therapy - July 5, 2018 Category: Rheumatology Authors: Joseph Hutton, Tahzeeb Fatima, Tanya J. Major, Ruth Topless, Lisa K. Stamp, Tony R. Merriman and Nicola Dalbeth Tags: Research article Source Type: research