First, We Need To Talk: Mental Healthcare In The MENA Region

The Middle East and North Africa (MENA) face daunting challenges in managing a growing burden of mental illness, often in adverse conditions that can leave their imprint on generations to come.While the burden of mental-health conditions is above the global average in most MENA countries, the human resources, policies, funding and infrastructure to deal with these problems are sorely lacking.According to a recent study led by the Institute for Health Metrics and Evaluation (IHME), mental disorders excluding substance abuse accounted for 4.7% of all disability-adjusted life years (DALYs) in the World Health Organization ’s (WHO) Eastern Mediterranean region (EMR) in 2015, making them the ninth leading cause of disease burden.That is below the average 9.3% of DALYs attributed to mental-health conditions in the Asia Pacific region. Moreover, WHO data indicate that neuropsychiatric disorders are responsible for 15.2% of all DALYs in Europe .The much larger burden in Europe, nonetheless, in particular reflects not only better visibility and understanding of mental disorders but lower levels of stigmatization and easier access to healthcare services where mental illness can be diagnosed, treated and recorded.The general lack of data on mental-health conditions in EMR countries, as well as the reluctance of many EMR citizens to present with such conditions for fear of social ostracism, mean estimates of prevalence and incidence across the region are likely to be substantially ...
Source: EyeForPharma - Category: Pharmaceuticals Authors: Source Type: news

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Publication date: Available online 22 June 2019Source: The Journal of Allergy and Clinical Immunology: In PracticeAuthor(s): Stephen Betschel, Ernie Avilla, Amin Kanani, Monika Kastner, Paul Keith, Karen Binkley, Gina Lacuesta, Rozita Borici-Mazi, Jacquie Badiou, Anne Rowe, William H. Yang, Susan WasermanAbstractBackgroundHAE patients present to the emergency department (ED), where their symptoms are often incorrectly attributed to common allergic and gastrointestinal conditions resulting in major delays in diagnosis and treatment.ObjectiveThe goal of this study was to develop a rapid triage HAE tool for ED settings.Method...
Source: The Journal of Allergy and Clinical Immunology: In Practice - Category: Allergy & Immunology Source Type: research
Operating before birth can minimize nerve damage caused by severe defects in tissue around the spinal column.
Source: NYT - Category: American Health Authors: Tags: Pregnancy and Childbirth Paralysis Birth Defects Spina Bifida Disabilities Spine (Body Part) Fetal surgery Texas Children ' s Hospital your-feed-healthcare Source Type: news
Publication date: August 2019Source: Research in Developmental Disabilities, Volume 91Author(s): Xiaomeng Chen, Lelin Liang, Minghui Lu, Miloň Potměšil, Jingxun ZhongAbstractThe purpose of this study was to examine the effects of reading mode (oral and silent reading) and braille reading patterns (one-handed pattern, mark pattern, parallel pattern, cooperative pattern) on the reading speed and comprehension of students with visual impairments in China. Seventy-three students with visual impairments aged 10–19 years participated in the study; 48 were students with congenital visual impairments and 25 were stu...
Source: Research in Developmental Disabilities - Category: Disability Source Type: research
Publication date: Available online 24 June 2019Source: Progress in Neuro-Psychopharmacology and Biological PsychiatryAuthor(s): Xinyu Fang, Yan Chen, Yewei Wang, Juanjuan Ren, Chen ZhangAbstractObjectivesDepressive symptoms are commonly seen in schizophrenia. Increasing evidence implicates that both SIRT1 and BDNF closely related to the development of depression. So we here aimed to explore the effect of BDNF and SIRT1 on the depressive symptoms, and also explore the hazard factors for the depression in schizophrenia.MethodsA group of 203 participants (case/controls, 174/29) was recruited in the present work. Significant d...
Source: Progress in Neuro Psychopharmacology and Biological Psychiatry - Category: Psychiatry Source Type: research
ConclusionReassurance seeking appears to be a common factor across anxiety disorders though the themes of the reassurance may differ. Further, reduction in excessive reassurance seeking may be an important component in treatment outcome.
Source: Journal of Anxiety Disorders - Category: Psychiatry Source Type: research
This study shows that it is possible to evoke NMDA-dependent epileptiform activity in prefrontal cortex pyramidal neurons in vitro.We suggest that the prefrontal cortex is a good region for studying the influence of drugs on interictal epileptiform activity.Graphical abstract
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 22 June 2019Source: Neuroscience LettersAuthor(s): Nastaran Rahimi, Mahsa Hassanipour, Fatemeh Yarmohammadi, Hedyeh Faghir-Ghanesefat, Nastaran Pourshadi, Erfan Bahramnejad, Ahmadreza DehpourAbstractThe neuro-protective effects of rubidium and lithium as alkali metals have been reported for different central nervous system dysfunctions including mania and depression. The aim of this study was evaluating as well as comparing the effects of rubidium chloride (RbCl) and lithium chloride (LiCl) on different seizures paradigms in mice and determining the involvement of NMDA receptors and nitre...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
This study aimed at investigating CPM magnitude in two distinct subgroups of healthy subjects, presenting low vs. high sensitivity to pain (LSP vs. HSP, respectively), by employing two different thermal paradigms of CPM.MethodNinety-five healthy subjects (out of 293 tested) were identified as LSP (n = 48) or HSP (n = 47) according to their tolerance time to noxious cold stimulation (Cold Pressor Test, 1 °C). All subjects were exposed to two different paradigms of CPM: 1) Fixed temperature ‘test-pain’ (TP) where phasic, fixed painful heat stimuli of 47 °C were ad...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
Publication date: Available online 22 June 2019Source: NeuroImageAuthor(s): Martin Sjøgård, Xavier De Tiège, Alison Mary, Philippe Peigneux, Serge Goldman, Guy Nagels, Jeroen van Schependom, Andrew J. Quinn, Mark Woolrich, Vincent WensAbstractThe default-mode network (DMN) and its principal core hubs in the posterior midline cortices (PMC), i.e., the precuneus and the posterior cingulate cortex, play a critical role in the human brain structural and functional architecture. Because of their centrality, they are affected by a wide spectrum of brain disorders, e.g., Alzheimer's disease. Non-invasive elect...
Source: NeuroImage - Category: Neuroscience Source Type: research
Publication date: Available online 22 June 2019Source: The Annals of Thoracic SurgeryAuthor(s): Dmitry B. Giller, Galina V. Giller, Boris D. Giller, Alexander V. Papkov, Galina V. Scherbakova, Vadim V. Koroev, Oleg Sh. KesaevAbstractA patient with extensive fibro-cavitary pulmonary tuberculosis (TB) and extensively drug-resistant (XDR) Mycobacterium tuberculosis (MTB) underwent bilateral VATS thoracoplasty. An examination four years post-surgery revealed that the patient was in a satisfactory condition and able-bodied.We performed surgery according to our proposed VATS thoracoplasty technique. In the postoperative period, ...
Source: The Annals of Thoracic Surgery - Category: Cardiovascular & Thoracic Surgery Source Type: research
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