Flavanols are potential anti-obesity agents, a systematic review and meta-analysis of controlled clinical trials

Publication date: July 2018Source: Nutrition, Metabolism and Cardiovascular Diseases, Volume 28, Issue 7Author(s): M. Akhlaghi, S. Ghobadi, M. Mohammad Hosseini, Z. Gholami, F. MohammadianAbstractBackgroundThe anti-obesity potential of flavonoids has been shown by animal and human studies. In this meta-analysis, we systematically reviewed controlled clinical trials and quantified the effects of flavonoids and flavonoid subclasses on obesity-related anthropometric measures.Methods and resultsPubMed, EMBASE, Scopus, Web of Science, and ProQuest databases were searched to identify trials examining the effect of flavonoids on body mass index (BMI), waist circumference, and body fat percentage. Fifty eight trials passed the eligibility process. Analysis endpoints were calculated as the mean difference between baseline and post-treatment. Flavonoids were in subclasses of flavanols, flavonols, isoflavones, flavanones, anthocyanins, and proanthocyanidins. They were mostly in the form of supplements and dosages varying from 40 to 1300 mg/day. Among flavonoid subclasses, flavanols showed potential for decreasing BMI, in the overall population (mean difference (MD) = −0.28 kg/m2, P = 0.04; n = 21) and in the subgroups of Asians (MD = −0.42 kg/m2; P = 0.046; n = 13), ages 
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research

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Conclusions: the prevalence found was higher than that of other national researches, especially for the female gender. In the male gender, not having internet access, a lesser number of family members and a longer screen time proved to be factors associated with being excess weight.Resumo Objetivos: investigar a preval ência de excesso de peso e fatores associados entre adolescentes de uma comunidade de baixa renda situada na cidade do Recife, Pernambuco. Métodos: estudo transversal, em que foram coletadas informações demográficas, socioeconômicas e comportamentais no período ...
Source: Revista Brasileira de Saude Materno Infantil - Category: Midwifery Source Type: research
Conclusion: The present study indicates a downward secular trend in the menarcheal age of the Saudi population. Moreover, a negative correlation between BMI and menarcheal age was also documented. PMID: 31522226 [PubMed - in process]
Source: Saudi Medical Journal - Category: Middle East Health Tags: Saudi Med J Source Type: research
Publication date: Available online 16 September 2019Source: The American Journal of SurgeryAuthor(s): Minyoung Kwak, J. Hunter Mehaffey, Robert B. Hawkins, Angel Hsu, Bruce Schirmer, Peter T. HallowellAbstractIntroductionObesity is a risk factor for non-alcoholic steatohepatitis (NASH) and hepatocellular carcinoma (HCC). Bariatric surgery can provide durable weight-loss, but little is known about the later development of NASH and HCC after surgery.MethodsBariatric surgery (n=3,410) and obese controls (n=46,873) from an institutional data repository were propensity score matched 1:1 by demographics, comorbidities, BMI, and ...
Source: The American Journal of Surgery - Category: Surgery Source Type: research
Conditions:   Obesity;   Morbid Obesity;   Diabetes Mellitus, Type 2;   Atrial Fibrillation Intervention:   Behavioral: Intermittent Fasting Sponsor:   University of Chicago Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Obesity Interventions:   Behavioral: Project Health;   Other: Educational Video Control Sponsor:   University of Houston Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: De Jong A, Verzilli D, Chanques G, Futier E, Jaber S Abstract The obese patient is at an increased risk of perioperative complications. Most importantly, these include difficult access to the airways (intubation, difficult or impossible ventilation), and post-extubation respiratory distress secondary to the development of atelectasis or obstruction of the airways, sometimes associated with the use of morphine derivatives. The association of obstructive sleep apnea syndrome (OSA) with obesity is very common, and induces a high risk of peri- and postoperative complications. Preoperative OSA screening is cruc...
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Authors: Lemyze M, Granier M Abstract As a result of the constantly increasing epidemic of obesity, it has become a common problem in the intensive care unit. Morbid obesity has numerous consequences for the respiratory system. It affects both respiratory mechanics and pulmonary gas exchange, and dramatically impacts on the patient's management and outcome. With the potential for causing devastating respiratory complications, the particular anatomical and physiological characteristics of the respiratory system of the morbidly obese subject should be carefully taken into consideration. The present article reviews th...
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
Authors: Cuvelier A, Taillé C PMID: 31521431 [PubMed - as supplied by publisher]
Source: Revue des Maladies Respiratoires - Category: Respiratory Medicine Tags: Rev Mal Respir Source Type: research
This report outlines recommendations for transforming the street environment, particularly around schools, with the ambition that all children should have access to a healthy route home.
Source: Current Awareness Service for Health (CASH) - Category: Consumer Health News Source Type: news
"These latest data shout that our national obesity crisis is getting worse," says the CEO of a nonprofit organization that publishes an annual report on the state of obesity in America.Medscape Medical News
Source: Medscape Medical News Headlines - Category: Consumer Health News Tags: Diabetes & Endocrinology News Source Type: news
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