Leptin to Adiponectin ratio – a surrogate biomarker for early detection of metabolic disturbances in obesity

ConclusionL:A ratio was able to detect early metabolic disturbances in obese individuals, and may be a potential useful clinical surrogate biomarker of metabolic disorders.
Source: Nutrition, Metabolism and Cardiovascular Diseases - Category: Nutrition Source Type: research

Related Links:

Infants and toddlers should not be given soda, chocolate milk or other sweetened drinks, according to strict new guidelines.
Source: NYT Health - Category: Consumer Health News Authors: Tags: Children and Childhood Milk Juices Infant Formulas Obesity Water Diet and Nutrition Babies and Infants Sugar Weight Caffeine Baby Foods Calories Soft Drinks Artificial Sweeteners Diabetes Heart your-feed-science your-fe Source Type: news
Publication date: Available online 17 September 2019Source: Molecular and Cellular EndocrinologyAuthor(s): Galyna V. Graham, Andrew McCloskey, Yasser H. Abdel-Wahab, J. Michael Conlon, Peter R. FlattAbstractPeptidase-resistant analogues of GLP-1 peptides from sea lamprey and paddlefish ([D-Ala2]palmitoyl-lamprey GLP-1 and [D-Ala2]palmitoyl-paddlefish GLP-1) produced significant (P ≤ 0.05) and concentration-dependent increases in insulin release from BRIN-BD11 clonal β-cells and from isolated mouse islets. Both analogues retained the ability of the native peptides to activate both the GLP-1 receptor (GLP1R) and ...
Source: Molecular and Cellular Endocrinology - Category: Endocrinology Source Type: research
Publication date: October 2019Source: Canadian Journal of Diabetes, Volume 43, Issue 7, SupplementAuthor(s): Matea Belan, Belina Carranza-Mamane, Youssef Ainmelk, Marie-Hélène Pesant, Karine Duval, Farrah Jean-Denis, Marie-France Langlois, Jean-Patrice Baillargeon
Source: Canadian Journal of Diabetes - Category: Endocrinology Source Type: research
GENERAL PURPOSE To provide information on obesity, bariatric surgery, and the nutrient deficiency-related dermatoses that may result from these surgeries. TARGET AUDIENCE This continuing education activity is intended for physicians, physician assistants, NPs, and nurses with an interest in skin and wound care. LEARNING OBJECTIVES/OUTCOMES After participating in this educational activity, the participant should be better able to: 1. Examine issues related to obesity and bariatric surgery. 2. Identify the sources and role of specific nutrients. 3. Recognize the clinical signs and symptoms of nutrient deficiency f...
Source: Advances in Skin and Wound Care - Category: Dermatology Tags: FEATURES: CLINICAL MANAGEMENT EXTRA Source Type: research
Setting aside the mice genetically engineered to destroy senescent cells, the combination of dasatinib and quercetin is the oldest of the senolytic treatments used in animal studies. Senolytic therapies are those that selectively destroy senescent cells in old tissues in order to produce rejuvenation, turning back the progression of numerous age-related conditions. Unusually for early stage research, these initial senolytics are actually quite effective, considered in the grand scheme of things. Thus they have moved directly to human trials in some cases. The first data on their ability to produce the same outcomes in huma...
Source: Fight Aging! - Category: Research Authors: Tags: Medicine, Biotech, Research Source Type: blogs
People with obesity or severe obesity are 60 percent more likely to have chronic diarrhea than those with normal BMI, according to a study that suggests BMI is important to consider when treating abnormal bowel habits.
Source: Health News - UPI.com - Category: Consumer Health News Source Type: news
Scientists from the Shanghai Jiao Tong University School of Medicine analysed more than 1,000 people with atherosclerosis, which occurs when fatty deposits clog the arteries.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Authors: Iyer KS, Dayal S Abstract Platelets are small, anucleated effector cells that play an important role in linking the hemostatic and inflammatory processes in the body. Platelet function is known to be altered under various inflammatory conditions including aging. A gain in platelet function during aging can increase the risk of thrombotic events, such as stroke and acute myocardial infarction. Anti-platelet therapy is designed to reduce risk of serious cerebrovascular and cardiovascular events, but the adverse consequences of therapy, such as risk for bleeding increases with aging as well. Age-associated co...
Source: Platelets - Category: Hematology Tags: Platelets Source Type: research
This study determined, if increased intrauterine oxidative stress (IUOx) affects adiposity, glucose and cholesterol metabolism in adult Ldlr−/−xSod2+/+ offspring from crossing male Ldlr−/−xSod2+/+ mice with Ldlr−/−xSod2 ± dams (IUOx) or Ldlr−/−xSod2 ± males with Ldlr−/−xSod2+/+ dams (control). At 12 weeks of age mice received Western diet for an additional 12 weeks. Adult male IUOx offspring displayed lower body weight and reduced adiposity associated with improved glucose tolerance compared to controls. Reduced weight gain in IUO...
Source: Redox Biology - Category: Biology Source Type: research
Publication date: Available online 17 September 2019Source: PeptidesAuthor(s): Vincent MarksAbstractThis paper describes the early history of Gastric Inhibitory Polypeptide, better referred to simply as GIP, from its isolation by purification from a crude preparation of CCK-PZ (cholecystokinin/pancreozymin) to its recognition as a key play in the pathogenesis of obesity and other metabolic disorders far removed from the enterogastrone properties by which it was originally identified. Augmentation of glucose mediated insulin release, the incretin effect, was discovered soon after GIP was first isolated and only much later w...
Source: Peptides - Category: Biochemistry Source Type: research
More News: Cardiology | Cardiovascular | Eating Disorders & Weight Management | Heart | Insulin | Nutrition | Obesity | Study