Double-blind evaluation of homeopathy on cocaine craving: a randomized controlled pilot study

This study investigates the effectiveness and tolerability of homeopathic Q-potencies of opium and E. coca in the integrative treatment of cocaine craving in a community-based psychosocial rehabilitation setting.Design, setting, participants, and interventionsA randomized, double-blind, placebo-controlled, parallel-group, eight-week pilot trial was performed at the Psychosocial Attention Center for Alcohol and Other Drugs (CAPS-AD), Sao Carlos/SP, Brazil. Eligible subjects included CAPS-AD patients between 18 and 65 years of age, with an International Classification of Diseases-10 diagnosis of cocaine dependence (F14.2). The patients were randomly assigned to two treatment groups: psychosocial rehabilitation plus homeopathic Q-potencies of opium and E. coca (homeopathy group), and psychosocial rehabilitation plus indistinguishable placebo (placebo group).Main outcome measuresThe main outcome measure was the percentage of cocaine-using days. Secondary measures were the Minnesota Cocaine Craving Scale and 12-Item Short-Form Health Survey scores. Adverse events were reported in both groups.ResultsThe study population comprised 54 patients who attended at least one post-baseline assessment, out of the 104 subjects initially enrolled. The mean percentage of cocaine-using days in the homeopathy group was 18.1% (standard deviation (SD): 22.3%), compared to 29.8% (SD: 30.6%) in the placebo group (P 
Source: Journal of Integrative Medicine - Category: Complementary Medicine Source Type: research

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See something of interest? Please share our postings with colleagues in your institutions! Spotlight September is National Preparedness Month. Disasters Happen. Prepare Now. Learn How. This week: Check your coverage. The Fall 2018 offering for The Health Sciences Library Association of New Jersey’s Group Licensing Initiative (HSLANJ GLI) is now available. MAR members are eligible for this cost-saving opportunity! The deadline to participate is Friday, November 9. Learn more. National Network of Libraries of Medicine News Funding Available: NNLM MAR has funding available for two grants of $19,000. Libraries, community...
Source: NN/LM Middle Atlantic Region Blog - Category: Databases & Libraries Authors: Tags: Weekly Postings Source Type: news
Behavioral approaches are the main treatments for methamphetamine (MA) use disorder, and although they can be effective, many patients relapse (Vocci and Appel, 2007). Despite a number of clinical trials testing the efficacy of agents including dopamine partial agonists and GABAergic and serotonergic agents, there are no approved pharmacological treatments for MA use disorder (Elkashef et al., 2008; Karila et al., 2010). Early abstinence from MA is accompanied by intense drug craving and high levels of cognitive impairment (Potvin et al., 2018; Zorick et al., 2010), which are important factors in the maintenance of addicti...
Source: Drug and Alcohol Dependence - Category: Addiction Authors: Tags: Full length article Source Type: research
Publication date: Available online 19 September 2018Source: Neuroscience &Biobehavioral ReviewsAuthor(s): Anita C. Hansson, Gerhard Gründer, Natalie Hirth, Hamid R. Noori, Rainer Spanagel, Wolfgang H. SommerAbstractA major hypothesis in the addiction field suggests deficits in dopamine signaling during abstinence as a driving mechanism for the relapsing course of the disorder. Paradoxically, blockade of mu-opioid receptors (MORs) intended to suppress dopamine release and alcohol reward is a widely used treatment for preventing relapse in alcohol use disorder (AUD). To elucidate this apparent discrepancy, we system...
Source: Neuroscience and Biobehavioral Reviews - Category: Neuroscience Source Type: research
Looking at Your Family History It can be widely speculated that addiction can be hereditary. If there are addicts in your family, it could be possible that their behaviors can be passed on to you, as well. When considering this, it is important to look at your family history, especially your parent’s. Numerous studies show the cause of addiction can be broken down to 50 percent genetic and 50 percent issues with coping skills. Further studies have shown that children of addicts are up to 8 times more likely to also develop an addiction. One study in particular took 231 individuals who had been clinically diagnosed wi...
Source: Cliffside Malibu - Category: Addiction Authors: Tags: Addiction Addiction Recovery Alcohol Alcoholism Depression Depression Treatment Drinking Drug Rehab Information Drug Treatment Dual Diagnosis and Eating Disorder Treatment Mental Health family family disease hereditary Source Type: blogs
Conclusion: Social media addiction was found in over one-thirds of subjects and majority had mild addiction.
Source: Indian Journal of Community Medicine - Category: International Medicine & Public Health Authors: Source Type: research
Addiction can be conceptualized as persistent choice of drugs over non-drug alternatives (Ahmed, 2010; Heyman, 2009; Rachlin, 1997). Choice is determined by the value of the reinforcers available (Rachlin, 1992). Understanding why, in some individuals or situations, the value of drug reinforcers surpasses that of non-drug alternatives could help explain addiction and provide clues for potential treatment strategies. The present study investigated, within an animal model, how one potential determinant of reinforcer value – economy type – affected the value of cocaine and a non-drug alternative reinforcer.
Source: Drug and Alcohol Dependence - Category: Addiction Authors: Tags: Full length article Source Type: research
Addiction Biology, EarlyView.
Source: Addiction Biology - Category: Addiction Authors: Source Type: research
Increasing evidence supports the role of appetite-regulating hormones in the pathophysiology of alcohol addiction. Amongst those, leptin and acylated ghrelin seem to play key roles in mediating craving and relapse (Hirth et al., 2016).
Source: Psychoneuroendocrinology - Category: Psychiatry Authors: Source Type: research
ABSTRACT OBJECTIVE To estimate the prevalence of smoking and associated factors among rural residents. METHODS This is a population-based, cross-sectional study of 1,519 individuals carried out in 2016. We randomly selected 24 of the 50 census tracts that make up the eight rural districts of the city of Pelotas, State of Rio Grande do Sul, Brazil. All individuals aged 18 years or more living in the randomly selected households were eligible. Smokers were all those who smoked ≥ 1 cigarette/day for at least one month or declared that they had stopped smoking for less than one month. The independent variables included soci...
Source: Revista de Saude Publica - Category: International Medicine & Public Health Source Type: research
“Drugs are a waste of time. They destroy your memory and your self-respect and everything that goes along with your self-esteem.” – Kurt Cobain I grew up in a close-knit, fairly religious family where children were seen and not heard, where mealtime meant everyone sat down together and exchanged pleasantries while enjoying the prepared-at-home repasts, complete with dessert. There was no distraction, either from television or radio, and the telephone ringing was a rare occurrence, quickly dispatched once the caller learned we were eating. In fact, nothing was so urgent back then. It was, indeed, a peacefu...
Source: Psych Central - Category: Psychiatry Authors: Tags: Addictions Substance Abuse Alcoholism Drug Abuse Opioid Addiction Source Type: news
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