Impact of Percutaneous Pulmonary Valve Implantation on the Timing of Reintervention for Right Ventricular Outflow Tract Dysfunction

Publication date: Available online 30 May 2018Source: Revista Española de Cardiología (English Edition)Author(s): Fernando de Torres-Alba, Gerrit Kaleschke, Helmut BaumgartnerAbstractTetralogy of Fallot (TOF) is the most common cyanotic congenital heart defect. Early surgical repair has dramatically improved the outcome of this condition. However, despite the success of contemporary approaches with early complete repair, these are far from being curative and late complications are frequent. The most common complication is right ventricle outflow tract (RVOT) dysfunction, affecting most patients in the form of pulmonary regurgitation, pulmonary stenosis, or both, and can lead to development of symptoms of exercise intolerance, arrhythmias, and sudden cardiac death. Optimal timing of restoration of RVOT functionality in asymptomatic patients with RVOT dysfunction after TOF repair is still a matter of debate. Percutaneous pulmonary valve implantation, introduced almost 2 decades ago, has become a major game-changer in the treatment of RVOT dysfunction. In this article we review the pathophysiology, the current indications, and treatment options for RVOT dysfunction in patients after TOF repair with a focus on the role of percutaneous pulmonary valve implantation in the therapeutic approach to these patients.ResumenLa tetralogía de Fallot (TDF) es la cardiopatía congénita cianótica más frecuente. La reparación quirúrgica temprana ha mejorado radicalmente su pronóstico. ...
Source: Revista Espanola de Cardiologia - Category: Cardiology Source Type: research