Myasthenia gravis after allogeneic bone marrow transplantation: A case report and literature review

Publication date: Available online 18 May 2017Source: Hematology/Oncology and Stem Cell TherapyAuthor(s): Yutaka Tsutsumi, Takashi Kamiishi, Ryo Kikuchi, Shinichi Ito, Satomi Matsuoka, Takanori TeshimaAbstractA 52-year-old man with acute myeloid leukemia underwent allogeneic hematopoietic stem cell transplantation and developed extensive chronic graft-versus-host disease and myasthenia gravis (MG), which became involved with oculobulbar and proximal upper and lower limb weakness in 677 days. In the literature, we identified 24 cases where MG developed after allo-SCT. Graft-versus-host disease development and male recipients of female donors might be prone to the development of posttransplant MG (odds ratio, 3.75).
Source: Hematology Oncology and Stem Cell Therapy - Category: Cancer & Oncology Source Type: research