Role of 18F-FDG PET/CT in post-operative assessment and therapeutic follow up of renal cell carcinoma

Conclusion18F-FDG PET/CT is more accurate than CT in post-operative and therapeutic follow up of renal cell carcinoma.
Source: The Egyptian Journal of Radiology and Nuclear Medicine - Category: Nuclear Medicine Source Type: research

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CONCLUSIONS: The CCP score has potential prognostic value in predicting metastatic progression and might be a useful tool for the management of patients with RCC. PATIENT SUMMARY: In this study we looked at the utility of a particular gene expression profile from kidney tumors. We found that this gene expression test has the potential to identify tumors at risk of metastasis and thus could be a useful tool in the management of patients with kidney tumors. PMID: 32081562 [PubMed - as supplied by publisher]
Source: Urologic Oncology - Category: Urology & Nephrology Authors: Tags: Urol Oncol Source Type: research
We report the case of a 15-year-old girl presenting with distended abdomen, left flank pain, and a history of weight loss. Computed tomography showed a large tumor involving the left kidney that was initially diagnosed as renal cell carcinoma. She underwent exploratory open laparotomy and left radical nephrectomy followed by chemotherapy and showed good response. Histology of the resected tumor revealed features of Ewing's sarcoma of the kidney which was confirmed by molecular studies. This disease is rare, particularly in the pediatric population, and this report will help better understand the potential disease course an...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
We report the case of a 15-year-old girl presenting with distended abdomen, left flank pain, and a history of weight loss. Computed tomography showed a large tumor involving the left kidney that was initially diagnosed as renal cell carcinoma. She underwent exploratory open laparotomy and left radical nephrectomy followed by chemotherapy and showed good response. Histology of the resected tumor revealed features of Ewing’s sarcoma of the kidney which was confirmed by molecular studies. This disease is rare, particularly in the pediatric population, and this report will help better understand the potential disease cou...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
In conclusion, we showed that CA8 promoted RCC cell proliferation and migration, but it was down-regulated in RCC, which requires an additional mechanism study. PMID: 31715371 [PubMed - as supplied by publisher]
Source: Biomedicine and pharmacotherapy = Biomedecine and pharmacotherapie - Category: Drugs & Pharmacology Authors: Tags: Biomed Pharmacother Source Type: research
Conclusion: The current adjuvant chemotherapy used in sRCC patients who develop metastasis gives no survival advantage.
Source: Urology Annals - Category: Urology & Nephrology Authors: Source Type: research
Purpose of review Summarize current evidence for cytoreductive nephrectomy in patients with metastatic renal cell carcinoma (mRCC) of variant histology. Recent findings The mainstream treatment for advanced malignancy is systematic therapy, including chemotherapy, targeted therapy, and immunotherapy. Nonetheless, cytoreductive nephrectomy has been used in the management of mRCC including variant (nonclear cell) histology. Prospective data supported cytoreductive nephrectomy for clear cell mRCC in the cytokine immunotherapy era in the late 1990s. In the targeted therapy era, the practice of cytoreductive nephrectomy in...
Source: Current Opinion in Urology - Category: Urology & Nephrology Tags: EVOLVING ROLE OF CYTOREDUCTIVE NEPHRECTOMY: Edited by Vitaly Margulis and A. Ari Hakimi Source Type: research
Publication date: Available online 10 July 2019Source: Urology Case ReportsAuthor(s): Ben Silverman, Joey Levy, Alexandra S. Vagasi, Rosemary Purrazzella, Shahriyour AndazAbstractPrimary renal lymphoma (PRL) is a rare disease process which represents less than 1% of all renal masses and is an uncommon type of Non-Hodgkin’s Lymphoma. PRL is of clinical significance due to the fact that unlike the more commonly seen renal cell carcinoma, PRL is treated with neoadjuvant chemotherapy followed by nephrectomy. This challenges the long held notion that preoperative biopsies are not necessary prior to nephrectomy for renal m...
Source: Urology Case Reports - Category: Urology & Nephrology Source Type: research
ConclusionThis case highlights the unique behavior of chRCC with an unusual site of metastasis, and the necessity of long-term follow-up after primary tumor removal, even if it is known for a low-grade metastatic potential and a relatively good prognosis.
Source: International Journal of Surgery Case Reports - Category: Surgery Source Type: research
We present our first case of a patient incidentally found to have a solitary pancreatic metastatic renal cell carcinoma (RCC), following left nephrectomy for kidney cancer 15 years ago. He underwent laparoscopic SVSP-extended distal pancreatectomy (EDP). Final histopathology confirmed the diagnosis and margins were clear. He made a good recovery and despite loosing >70% of his pancreas, hasn't developed new-onset diabetes. No adjuvant chemotherapy was necessary, but he will require long-term follow-up. This case suggests that even when the pancreatic lesion is located more proximally, near or at the pancreatic ...
Source: Journal of Minimal Access Surgery - Category: Surgery Authors: Source Type: research
ConclusionsEven if cancer-to-cancer metastasis is a  very rare phenomenon, the simultaneous or consecutive finding of a renal tumor in women with breast cancer should be carefully evaluated.
Source: Wiener Medizinische Wochenschrift - Category: General Medicine Source Type: research
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