Developing a grouped random parameters multivariate spatial model to explore zonal effects for segment and intersection crash modeling

Publication date: September 2018Source: Analytic Methods in Accident Research, Volume 19Author(s): Qing Cai, Mohamed Abdel-Aty, Jaeyoung Lee, Ling Wang, Xuesong WangAbstractIt is acknowledged that crash occurrence on segments and intersections could be affected by multilevel factors. Omission of important explanatory variables could result in biased and inconsistent parameter estimates. This paper contributes to the literature by examining the zonal effects which are always excluded or ignored in traffic safety research for segments and intersections. A grouped random parameters multivariate spatial model is proposed to identify both observable zonal effects and unobserved heterogeneity at the zonal level by considering the heterogeneous and spatial correlations. The proposed model is evaluated by comparing it with its three counterparts: a fixed parameters univariate spatial model without zonal factors, a random parameters univariate spatial model without zonal factors, and a random parameters univariate spatial model with zonal factors. The results indicate that the three random parameters models could consistently provide better performance than the fixed parameters model and the models including zonal factors outperform the models without zonal factors. Besides, the proposed model has the optimal model performance compared with its counterparts, which validates the concept of adopting the multivariate modeling framework to identify the heterogeneous and spatial correlatio...
Source: Analytic Methods in Accident Research - Category: Accident Prevention Source Type: research

Related Links:

This study compared treatment failures between patients treated exclusively with IV antibiotics and those transitioned from IV to oral antibiotics for bacteraemia secondary to UTI.MethodsThis single-centre, retrospective cohort study included hospitalised, non-critically ill adult patients treated with culture-susceptible antibiotic therapy for 7–21 days. Patients were divided into two cohorts based on the route of definitive antibiotic administration. Treatment failure was a composite outcome of death and recurrence of the index micro-organism within 21 days following negative blood cultures.Results and discussionAm...
Source: Journal of Global Antimicrobial Resistance - Category: Infectious Diseases Source Type: research
Source: Annals of Hematology - Category: Hematology Source Type: research
Source: Annals of Hematology - Category: Hematology Source Type: research
Source: Annals of Hematology - Category: Hematology Source Type: research
Source: Annals of Hematology - Category: Hematology Source Type: research
AbstractAplastic anemia (AA) has been reported to be associated with inflammatory bowel disease (IBD), but mostly with ulcerative colitis (UC). Little is known about the associations between AA and Crohn ’s disease (CD). We aim to determine the portraits of patients with AA-CD. Among a total of 657 patients with CD registered in Xijing Hospital of Digestive Diseases IBD center from January 2008 to October 2018, the patients diagnosed with concurrent AA were reviewed. Clinical presentation, medical history, endoscopic features, response to treatment, and prognosis in this set of patients were collected. Six male patie...
Source: Annals of Hematology - Category: Hematology Source Type: research
AbstractNodal peripheral T cell lymphomas (nPTCL) present aggressive clinical course, and its heterogeneous nature and poor prognosis with current therapeutic strategies make it a target for the development of new prognostic markers. Thus, we investigated tumor-associated macrophages (TAM) according to the number of cells expressing CD68 in biopsies and the absolute monocyte count (AMC) in peripheral blood of 87 patients with nPTCL. The median overall survival (OS) was 3  years (95% CI 1.3–8.4 years) and estimate 5 years OS of 43.3% (95% CI 32.5–53.7%). The median progression-free survival (PFS) ...
Source: Annals of Hematology - Category: Hematology Source Type: research
AbstractIncidence and outcome of microbiologically documented bacterial/viral infections and invasive fungal disease (IFD) in children and adults after hematopoietic cell transplantation (HCT) were compared in 650 children and 3200 adults in multicenter cross-sectional nationwide study. Infections were diagnosed in 60.8% children and 35.0% adults, including respectively 69.1% and 63.5% allo-HCT, and 33.1% and 20.8% auto-HCT patients. The incidence of bacterial infections was higher in children (36.0% vs 27.6%;p 
Source: Annals of Hematology - Category: Hematology Source Type: research
In conclusion, efficacy data, the reassuring safety profile, and the novel mechanism of action of plitidepsin suggest that this combination can be an alternative option in patients with relapsed/refractory multiple myeloma after at least three prior therapy lines.
Source: Annals of Hematology - Category: Hematology Source Type: research
Source: Annals of Hematology - Category: Hematology Source Type: research
More News: Accident Prevention | Accidents | Statistics