DNA Methylation in Stroke. Update of Latest Advances

Publication date: 2018Source: Computational and Structural Biotechnology Journal, Volume 16Author(s): Jerzy Krupinski, Caty Carrera, Elena Muiño, Nuria Torres, Raid Al-Baradie, Natalia Cullell, Israel Fernandez-CadenasAbstractEpigenetic modifications are hereditable and modifiable factors that do not alter the DNA sequence. These epigenetic factors include DNA methylation, acetylation of histones and non-coding RNAs. Epigenetic factors have mainly been associated with cancer but also with other diseases and conditions such as diabetes or obesity. In addition, epigenetic modifications could play an important role in cardiovascular diseases, including stroke. We review the latest advances in stroke epigenetics, focusing on DNA methylation studies and the future perspectives in this field.
Source: Computational and Structural Biotechnology Journal - Category: Biotechnology Source Type: research