DEPTOR regulates osteogenic differentiation via inhibiting MEG3-mediated activation of BMP4 signaling and is involved in osteoporosis

The mammalian target of rapamycin (mTOR) pathway plays a significant role in osteogenic differentiation and bone maintenance. As the only known endogenous inhibitor of mTOR function, DEP domain containing mTOR...

Source: Stem Cell Research and Therapy - July 4, 2018 Category: Stem Cells Authors: Si Chen, Lingfei Jia, Shan Zhang, Yunfei Zheng and Yongsheng Zhou Tags: Research Source Type: research