Zerumbone from Zingiber zerumbet Ameliorates Lipopolysaccharide-Induced ICAM-1 and Cytokines Expression via p38 MAPK/JNK-I κB/NF-κB Pathway in Mouse Model of Acute Lung Injury.
In conclusion, zerumbone could be a potential protective agent for ALI, possibly via expression of ICAM-1, IL-1β, and MIP-2. The protective mechanism of zerumbone was by reversing the activation of p38 MAPK/JNK-IκB/NF-κB pathway.
PMID: 29962177 [PubMed - in process]
Source: The Chinese Journal of Physiology - Category: Physiology Tags: Chin J Physiol Source Type: research
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