Protamine to expedite vascular hemostasis after catheter ablation of atrial fibrillation: a randomized controlled trial

There are no randomized, controlled studies on the efficacy and safety of protamine sulfate to reverse anticoagulant effects of heparin after catheter ablation (CA) of atrial fibrillation (AF).
Source: Heart Rhythm - Category: Cardiology Authors: Source Type: research

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Publication date: Available online 20 November 2019Source: IJC Heart &VasculatureAuthor(s): Dominik Linz, Enrico Ammirati, Gheorghe-Andrei Dan, Jordi Heijman, Dobromir Dobrev
Source: IJC Heart and Vasculature - Category: Cardiology Source Type: research
Publication date: Available online 20 November 2019Source: Clinica Chimica ActaAuthor(s): Zhouqing Huang, Xiaohe Liang, Weiqi Wang, Zhijie Mao, Ya Lin, Lei Zhang, Zehao Jin, Shuang Lin, Wei Jiang Huang, Xiaokang HuAbstractBackgroundPrevious studies have shown that plasma cancer antigen-125 (CA-125) is closely related to heart failure and new-onset atrial fibrillation (AF), but no study reported the relationship between CA-125 concentrations and advanced recurrence of AF ablation. This research is the first to describe CA-125 as a biomarker for the recurrence of AF after ablation.MethodsA total of 422 AF patients undergoing...
Source: Clinica Chimica Acta - Category: Laboratory Medicine Source Type: research
Condition:   Cardiovascular Diseases Intervention:   Other: Treatment arm Sponsor:   Medtronic Cardiac Rhythm and Heart Failure Recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Li YM, Jiang C, He L, Li XX, Hou XX, Chang SS, Lip GYH, Du X, Dong JZ, Ma CS Abstract BACKGROUND There is a growing recognition of sex-related disparities in atrial fibrillation (AF). However, limited data is available in Chinese AF patients. MATERIAL AND METHODS We compared symptoms, quality of life (QoL), and treatment of AF according to sex from the China AF Registry study. RESULTS We studied 14 723 patients with non-valvular AF, of whom 5645 patients (38.3%) were female. Women were older than men (67.5±10.6 vs. 62.2±12.2). Compared to men, women had more comorbidities and a higher proport...
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Authors: Kaya H, Cavusoglu Y PMID: 31740358 [PubMed - as supplied by publisher]
Source: Hellenic Journal of Cardiology - Category: Cardiology Tags: Hellenic J Cardiol Source Type: research
This study was performed to assess whether presence of MAC and its severity predict cardio-embolic stroke in elderly patients with first diagnosed AF.Methods: In this cross-sectional study, 72 elderly patients suffering from acute cardio-embolic stroke with first diagnosed AF and 79 elderly control group patients with first diagnosed AF and without stroke were investigated. A parasternal short-axis view at the level of the mitral annulus was used for MAC measurements. The severity of MAC was measured from the anterior to posterior edge at its greatest width.Results: MAC thicknesses were significantly higher in the stroke g...
Source: Acta Cardiologica - Category: Cardiology Tags: Acta Cardiol Source Type: research
AbstractCatheter ablation is a  well-recognized treatment for a number of cardiac arrhythmias. Initially used to treat supraventricular tachycardia, this technique is now also widely used to treat ventricular arrhythmia and atrial fibrillation. This review aims to describe all the possible types of complication related to this i nvasive procedure. Definitions according to the current guidelines are provided, as are some details on the frequency of complications and how to diagnose and treat them appropriately. Finally, each section of the review provides guidance on how to prevent the complications associated with catheter ablation.
Source: Herzschrittmachertherapie und Elektrophysiologie - Category: Cardiology Source Type: research
The objective of this study was to assess differences in 30-day mortality in patients treated with DOACs or warfarin admitted to the emergency department (ED) for GIB. This was a multicentre retrospective study conducted over 2  years. The study included patients evaluated at three different EDs for GIB. The baseline characteristics were included. Subsequently, we assessed the differences in past medical history and clinical data between the two study groups (DOAC and warfarin users). Differences between the two groups we re evaluated using Kaplan–Meier curves. Among the 284 patients presenting GIB enrolled in t...
Source: Internal and Emergency Medicine - Category: Emergency Medicine Source Type: research
Condition:   Atrial Fibrillation Intervention:   Other: Periods of Apnea Sponsors:   Weill Medical College of Cornell University;   Northwell Health Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Publication date: Available online 19 November 2019Source: Pharmacological ResearchAuthor(s): Nebojša Mujović, Dobromir Dobrev, Milan Marinković, Vincenzo Russo, Tatjana S. PotparaAbstractAmiodarone is an iodinated benzofuran derivative, a highly lipophilic drug with unpredictable pharmacokinetics. Although originally classified as a class III agent due to its ability to prolong refractoriness in cardiac regions and prevent/terminate re-entry, amiodarone shows antiarrhythmic properties of all four antiarrhythmic drug classes. Amiodarone is a potent coronary and peripheral vasodilator and can be safely used in pati...
Source: Pharmacological Research - Category: Drugs & Pharmacology Source Type: research
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