Oxidative insults disrupt OPA1-mediated mitochondrial dynamics in cultured mammalian cells.

DISCUSSION: Taken together, these findings indicate that oxidative insults damage OPA1-mediated mitochondrial dynamics in mammalian cells via activation of OMA1, consistent with an emerging role for mitochondrial dynamics as an early indicator of cellular stress signaling. PMID: 29961397 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29961397?dopt=Abstract

Source: Redox Report : communications in free radical research - July 3, 2018 Category: Biochemistry Authors: Garcia I, Innis-Whitehouse W, Lopez A, Keniry M, Gilkerson R Tags: Redox Rep Source Type: research