Cancer Linked to Infertility in Men and Women

(MedPage Today) -- Assisted reproductive technology not to blame, researchers say
Source: MedPage Today Primary Care - Category: Primary Care Source Type: news

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AbstractBackgroundWhile the spermatotoxic properties of cancer treatments such as chemotherapy and radiation therapy are widely recognized, the effect of malignancy itself on male fertility is not clearly understood.ObjectivesTo determine whether malignancy is associated with diminished semen quality prior to spermatotoxic treatment among sperm bankers.Materials and MethodsRetrospective database review of de ‐identified records was obtained for all episodes of sperm banking performed at a cryobank from January 2004 to May 2017 for one of the following reasons: ‘future use’ (e.g., military deployment and gende...
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Original Article Source Type: research
(Natural News) You might remember that in 2012, The U.S. Food and Drug Administration (FDA) banned the sale of baby products that contained bisphenol-A (BPA). The ruling was made in response to the countless amount of data that showed that BPA was an endocrine disruptor associated with an increased risk of cancer, infertility, and other...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
Abstract The combination of doxorubicin and cyclophosphamide commonly used to treat breast cancer can cause premature ovarian failure and infertility. α-Tocopherol is a potent antioxidant whereas γ-tocopherol causes apoptosis in a variety of cancer models in vitro including breast cancer. We hypothesised that the combination of doxorubicin (Dox) and 4-hydroperoxycyclophosphamide (4-Cyc) would be more cytotoxic in vitro than each agent alone, and that α-tocopherol would reduce and γ-tocopherol would augment the cytotoxicity of the combined chemotherapeutics. Human MCF-7 breast cancer and KGN...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
(Natural News) Before ordering another drink, consider this: The American Society for Clinical Oncology (ASCO) warns us that alcohol can cause a higher risk for seven types of cancers. While it may seem harmless, light to moderate alcohol consumption can cause more than five percent of cancers and deaths from it. Not only that, the...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
ConclusionStudies of the effects of cannabis suggest impact on urologic health and disease. Prospective, long ‐term studies are necessary for further elucidation of these effects.
Source: Andrology - Category: Urology & Nephrology Authors: Tags: Review Article Source Type: research
UCLA Health Rates of sexually transmitted diseases have risen for the past four years to record highs in the United States, according to the Centers for Disease Control and Prevention ’slatest analysis. In California, the state health departmentfound that the number of people diagnosed with syphilis, gonorrhea or chlamydia in 2017 was 45 percent higher than five years prior.These sorts of statistics may spark a fear that there ’s little we can do to protect ourselves — but that’s not the full story.Dr. Leena Nathan, an obstetrician/gynecologist at UCLA Health-Westlake Village, consults with peo...
Source: UCLA Newsroom: Health Sciences - Category: Universities & Medical Training Source Type: news
A study by the University of Aberdeen also found that the breast-cancer drug tamoxifen - which blocks oestrogen from fueling a tumour's growth - has a positive effect on a man's swimmers.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
Abstract The ovarian steroid hormones, estrogen (E2) and progesterone (P4), are essential regulators of uterine biology. The imbalance of these ovarian steroid hormones leads to uterine diseases such as endometrial cancer, endometriosis, and infertility. Mitogen-inducible gene 6 (MIG-6) is an adaptor protein. MIG-6 mediates P4 signaling and acts as a tumor suppressor during endometrial tumorigenesis in both humans and mice. In previous studies, we developed the conditional knockout of Mig-6 in all uterine compartments (Pgrcre/+Mig-6f/f; Mig-6KO) and endometrial epithelial cell-specific Mig-6 knockout (Sprr2fcre/+M...
Source: Biochemical and Biophysical Research communications - Category: Biochemistry Authors: Tags: Biochem Biophys Res Commun Source Type: research
Over 10% of new cancer diagnoses occur in reproductive aged women, impacting 87 per 100,000 women each year [1]. Improvement in the management and treatment of these patients is leading to improved survival [2] and greater interest in survivorship outcomes. There is a growing movement to preserve the fullness of cancer patients ’ future. Satisfactory quality-of-life in cancer survivors may include the ability to conceive children and the infertility associated with cancer treatment can contribute to profound distress and depression in survivors [3].
Source: Biology of Blood and Marrow Transplantation - Category: Hematology Authors: Source Type: research
Abstract Chemotherapy-induced ovarian aging not only increases the risk for early menopause-related complications but also results in infertility in young female cancer survivors. Oogonial stem cells have the ability to generate new oocytes and thus provide new opportunities for treating ovarian aging and female infertility. Resveratrol (3,5,4'-trihydroxy-trans-stilbene) is a natural phenol derived from plants, that has been shown to have positive effects on longevity and redox flow in lipid metabolism and a preventive function against certain tumors. To evaluate whether resveratrol could promote the repair of oog...
Source: Aging - Category: Biomedical Science Authors: Tags: Aging (Albany NY) Source Type: research
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