Study Explores the Molecular Basis of Chronic Pain Following Nerve Injury

Researchers identifiy a key molecule, dual leucine zipper kinase (DLK), that controls pathways leading to chronic neuropathic pain following nerve injury.
Source: NCCAM Featured Content - Category: Complementary Medicine Authors: Source Type: news

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Publication date: Available online 14 December 2018Source: PeptidesAuthor(s): Alan R Gintzler, Nai-Jiang Liu, Emiliya M. Storman, Martin W. WessendorfAbstractEffective management of chronic pain is demanded by ethical as well as medical considerations. Although opioid analgesics remain among the most effective pharmacotherapies for ameliorating many types of pain, their use is clouded by concerns regarding their addictive properties, underscored by the current epidemic of prescription opioid abuse and attendant deaths. Medicinal harnessing of endogenous opioid antinociception could provide a strategy for continuing to take...
Source: Peptides - Category: Biochemistry Source Type: research
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Source: Lippincott's Bone and Joint Newsletter - Category: Orthopaedics Tags: Trends and Innovations Source Type: news
No abstract available
Source: Journal of Christian Nursing - Category: Nursing Tags: CE Connection Source Type: research
No abstract available
Source: Journal of Christian Nursing - Category: Nursing Tags: Department: Think About It Source Type: research
ABSTRACT: A significant portion of the world's population is impacted by chronic pain; in the United States, chronic pain costs billions annually in treatment and lost productivity. A needs assessment was conducted to evaluate the prevalence of chronic nonmalignant pain (CNMP) at a university occupational therapy clinic over a 3-month period; recommendations were made to improve pain management at the clinic and referring hospital system. Graded Chronic Pain Scale 2.0 results indicated the prevalence of CNMP was a significant problem. Three evidence-based interventions based on the biblically based CREATION Health Model were developed.
Source: Journal of Christian Nursing - Category: Nursing Tags: Feature: CE Connection: practice Source Type: research
Publication date: January 2019Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology, Volume 127, Issue 1Author(s): T.I. GHEORGHE, R. LEEKAM, E.W.N. LAM, S.E. PERSCHBACHER, B. LIEBGOTT, A.M.R. AGUREthical ReviewApproval for this study was received from the Health Sciences Research Ethics Board, University of Toronto (Toronto, ON, Canada).BackgroundThe masseter muscle (MM) is affected in conditions with chronic and acute facial pain. It has been suggested that architectural changes occur in the contractile and connective tissue elements of MM in these patients.1 Muscle architecture is defined as the arrangem...
Source: Oral Surgery, Oral Medicine, Oral Pathology and Oral Radiology - Category: ENT & OMF Source Type: research
In conclusion, the evidence from current research supports the use of medical cannabis in the treatment of chronic pain in adults. Careful follow-up and monitoring of patients using cannabis/cannabinoids are mandatory. PMID: 30542280 [PubMed]
Source: Pain Physician - Category: Anesthesiology Authors: Tags: Front Pharmacol Source Type: research
Authors: Yildirim D, Donmez T, Ozcevik H, Cakir M, Demiryas S, Akturk OM Abstract Introduction: Endoscopic hernia repair integrates the advantages of tension-free preperitoneal mesh support of the groin with the advantages of minimally invasive surgery procedures. Aim: To compare outcomes between slit mesh (SM) and nonslit mesh (NSM) placement in laparoscopic totally extraperitoneal (TEP) inguinal hernia repair. Material and methods: This is a retrospective study of 353 patients who underwent TEP inguinal hernia repair between January 2010 and December 2011. One hundred forty-nine and 154 hernias were opera...
Source: Videosurgery and Other Miniinvasive Techniques - Category: Surgery Tags: Wideochir Inne Tech Maloinwazyjne Source Type: research
(Natural News) Many people try massage for relaxation and pain relief. In Ayurveda, massage and physical therapy have often been used to treat patients with chronic pain syndromes and disorders of the musculoskeletal system. A study published in The Journal of Alternative and Complementary Medicine found that Ayurvedic massage is also a safe and effective...
Source: NaturalNews.com - Category: Consumer Health News Source Type: news
This study evaluated the attitudes, beliefs and level of pain neuroscience knowledge among Israeli Bachelor-level physiotherapy students.MethodsFirst-year (n = 29, before pain course), second-year (n = 28, immediately after pain course and before clinical placements), and fourth-year (n = 28, post-clinical placements) physiotherapy students completed the Health Care Providers’ Pain and Impairment Relationship Scale (HC-PAIRS, range 15–105, lower scores indicate a more positive attit ude) to assess pain attitudes and beliefs. The Neurophysiology of Pain Questionnaire (NP...
Source: Israel Journal of Health Policy Research - Category: International Medicine & Public Health Source Type: research
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