Critical Role for the Microbiota in CX3CR1+ Intestinal Mononuclear Phagocyte Regulation of Intestinal T  Cell Responses

Host microbiota interactions regulate many aspects of immunity. Kim et  al. demonstrate that microbial adhesion to intestinal epithelium helps regulate the balance between pro- and anti-inflammatory T cell responses through induction of IL-10 by a subset of intestinal antigen-presenting cells.

Source: Immunity - July 3, 2018 Category: Allergy & Immunology Authors: Myunghoo Kim, Carolina Galan, Andrea A. Hill, Wan-Jung Wu, Hannah Fehlner-Peach, Hyo Won Song, Deborah Schady, Matthew L. Bettini, Kenneth W. Simpson, Randy S. Longman, Dan R. Littman, Gretchen E. Diehl Tags: Article Source Type: research