Parcellating cognitive heterogeneity in early psychosis-spectrum illnesses: A cluster analysis

Cognitive impairment is argued to represent a core feature of psychosis-spectrum illnesses. However, within-diagnosis heterogeneity is common, and risk factors for poor cognition remain to be examined after statistically accounting for heterogeneity. Accordingly, we used a data-driven technique (cluster analysis) to empirically-derive cognitive clusters across diagnoses and examined whether concurrent substance use or a history of a neurodevelopmental/behavioral disorder differed between clusters.
Source: Schizophrenia Research - Category: Psychiatry Authors: Source Type: research