Influence of CYP2D6 Polymorphism on the Pharmacokinetic/Pharmacodynamic Characteristics of Carvedilol in Healthy Korean Volunteers.

Conclusion: These findings showed that CYP2D6 genotype influenced the PK characteristics of carvedilol and no differences in PD response were observed in Korean healthy volunteers. Registered at the ClinicalTrials.gov, NCT02286934. PMID: 29962926 [PubMed - in process]

https://www.ncbi.nlm.nih.gov/pubmed/29962926?dopt=Abstract

Source: J Korean Med Sci - July 2, 2018 Category: General Medicine Authors: Jung E, Ryu S, Park Z, Lee JG, Yi JY, Seo DW, Lee J, Jeong HS, Kim JM, Oh WY Tags: J Korean Med Sci Source Type: research