Comparison of Premortem Magnetic Resonance Imaging and Postmortem Autopsy Findings of a Cortical Microinfarct

An 85-year-old woman diagnosed with amyotrophic lateral sclerosis died of pneumonia and was autopsied. Magnetic resonance imaging (MRI) performed 16days before death revealed an intracortical high-intensity lesion in her right temporal cortex on three-dimensional (3D)-double inversion recovery (DIR) and 3D-fluid-attenuated inversion recovery (FLAIR) images. Histopathological examination indicated a cortical microinfarct (CMI) juxtaposed to cerebral amyloid angiopathy. Recently, in vivo detection of CMIs using 3D-DIR and 3D-FLAIR on 3-tesla MRI has been reported, and postmortem MRI study confirmed the presence of CMIs.
Source: Journal of Stroke and Cerebrovascular Diseases - Category: Neurology Authors: Source Type: research

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Publication date: Available online 22 February 2019Source: Respiratory Medicine Case ReportsAuthor(s): Ateeq Mubarik, Aamani Jupalli, Arshad Muhammad Iqbal, Sohaib Khaleel Mohammed, Salman Muddassir, Eddib AbdulmagidAbstractMycoplasma pneumoniae is one of the most common causes of community-acquired pneumonia in adults. Mycoplasma pneumoniae pneumonia (MPP) presents with pulmonary and extrapulmonary manifestations. Pneumothorax is a rare MPP complication in children. But, we reported a case of MPP with hydropneumothorax in an adult. The association of MPP, hydropneumothorax, and empyema is extremely rare.
Source: Respiratory Medicine Case Reports - Category: Respiratory Medicine Source Type: research
Publication date: Available online 22 February 2019Source: NeuroImage: ClinicalAuthor(s): Benedikt Figel, Leonie Brinkmann, Christine Buff, Carina Y. Heitmann, David Hofmann, Maximilian Bruchmann, Michael P.I. Becker, Martin J. Herrmann, Thomas StraubeAbstractAnticipation of potentially threatening social situations is a key process in social anxiety disorder (SAD). In other anxiety disorders, recent research of neural correlates of anticipation of temporally unpredictable threat suggests a temporally dissociable involvement of amygdala and bed nucleus of the stria terminalis (BNST) with phasic amygdala responses and susta...
Source: NeuroImage: Clinical - Category: Radiology Source Type: research
Abstract The stroke-prone spontaneously hypertensive rat (SHRSP) suffers from severe hypertension and hypertensive organ damage such as cerebral stroke and kidney injury under salt-loading. By a quantitative trait locus (QTL) analysis between SHRSP and SHR (the stroke-resistant parental strain of SHRSP), two major QTLs for stroke susceptibility were identified on chromosomes 1 and 18 of SHRSP, which were confirmed in congenic strains constructed between SHRSP and SHR. As the progression of renal dysfunction was suggested to be one of the key factors inducing stroke in SHRSP, we examined effects of the stroke-relat...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Int Source Type: research
Abstract One of the most severe complications of lung resection is postoperative pneumonia, and its prevention and prediction are critical. Exhaled acetone and isoprene are thought to be related to metabolism; however, little is known on their relationship with bacteria living in the oral cavity or their meaning in the acute phase in perioperative lung cancer patients. We measured acetone and isoprene in exhaled breath of 13 Japanese patients with lung cancer (3 women and 10 men, age range 62-82 years, mean 72.4 years) before breakfast during hospitalization, and compared with two acute-phase proteins, C-reactive ...
Source: Biomed Res - Category: Research Authors: Tags: Biomed Res Source Type: research
Publication date: Available online 23 February 2019Source: The Journal of Foot and Ankle SurgeryAuthor(s): İbrahim Alper Yavuz, Ahmet Ozgur Yildirim, Ozdamar Fuad Oken, Erman Ceyhan, Fatih İnci, Ozlem Ozkale Yavuz, Deniz Sozmen CılızAbstractLong-term studies have shown that 10% to 20% of patients continue to experience ankle pain years after tibial fracture, which causes poor functional results and dissatisfaction. The aim of this study was to show that there could be a talus injury in patients with a tibial shaft fracture and to reveal occult talus lesions with magnetic resonance imaging (MRI) examination. Fifty-two p...
Source: The Journal of Foot and Ankle Surgery - Category: Orthopaedics Source Type: research
Publication date: Available online 22 February 2019Source: Journal of the Academy of Nutrition and DieteticsAuthor(s): Matthew J. Landry, Fiona M. Asigbee, Sarvenaz Vandyousefi, Erfan Khazaee, Reem Ghaddar, Jessica B. Boisseau, Benjamin T. House, Jaimie N. DavisAbstractBackgroundNo studies have assessed the relationship between diet quality, using the Healthy Eating Index (HEI), and adiposity, physical activity, and metabolic disease risk factors in a Hispanic college population.ObjectiveTo assess associations between diet quality and adiposity, metabolic health, and physical activity levels in a Hispanic college freshman ...
Source: Journal of the Academy of Nutrition and Dietetics - Category: Nutrition Source Type: research
ConclusionThis study highlights the ongoing risk of opportunistic infection several years after transplantation and adds weight to potential person to person Pneumocystis jirovecii transmission. Risk factors have been identified which may highlight those most at risk, allowing targeted rather than blanket long-term PCP prophylaxis.
Source: Journal of Hospital Infection - Category: Infectious Diseases Source Type: research
CONCLUSIONS OGD could induce the over-activation of autophagy and augment the apoptotic activity in neurons and glial cells of NVUs. PMID: 30787267 [PubMed - in process]
Source: Medical Science Monitor - Category: Research Tags: Med Sci Monit Source Type: research
Publication date: Available online 22 February 2019Source: Biocybernetics and Biomedical EngineeringAuthor(s): P. Sriramakrishnan, T. Kalaiselvi, R. RajeswaranAbstractThe proposed work develops a rapid and automatic method for brain tumour detection and segmentation using multi-sequence magnetic resonance imaging (MRI) datasets available from BraTS. The proposed method consists of three phases: tumourous slice detection, tumour extraction and tumour substructures segmentation. In phase 1, feature blocks and SVM classifier are used to classify the MRI slices into normal or tumourous. Phase 2 contains fuzzy c means (FCM) alg...
Source: Biocybernetics and Biomedical Engineering - Category: Biomedical Engineering Source Type: research
Publication date: 1 May 2019Source: NeuroImage, Volume 191Author(s): Anne C. Trutti, Martijn J. Mulder, Bernhard Hommel, Birte U. ForstmannAbstractThe ventral tegmental area (VTA) and substantia nigra pars compacta (SNc) are assumed to play a key role in dopamine-related functions such as reward-related behaviour, motivation, addiction and motor functioning. Although dopamine-producing midbrain structures are bordering, they show significant differences in structure and function that argue for a distinction when studying the functions of the dopaminergic midbrain, especially by means of neuroimaging. First, unlike the SNc,...
Source: NeuroImage - Category: Neuroscience Source Type: research
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