Impact of lung function on bronchiolitis obliterans syndrome and outcome after allogeneic hematopoietic cell transplantation with reduced intensity conditioning

Pulmonary dysfunction is one of the major causes of non-relapse mortality in patients undergoing allogeneic hematopoietic cell transplantation (allo-HCT). It requires a wide differential diagnosis and has been linked to chemotherapy toxicity, irradiation, infections, immune-induced injury by Graft-versus-Host-Disease (GvHD) and restrictive lung diseases [1,2].

https://www.bbmt.org/article/S1083-8791(18)30361-6/fulltext?rss=yes

Source: Biology of Blood and Marrow Transplantation - July 2, 2018 Category: Hematology Authors: Jes ús Duque-Afonso, Gabriele Ihorst, Miguel Waterhouse, Robert Zeiser, Ralph Wäsch, Hartmut Bertz, Joachim Müller-Quernheim, Jürgen Finke, Reinhard Marks, Antje Prasse Source Type: research