Pulmonary Circulation on the Crossroads Between the Left and Right Heart in Systemic Sclerosis
Involvement of the right heart –pulmonary circulation system in systemic sclerosis is a typical feature, with critical prognostic implications. Pulmonary hypertension may occur in association with interstitial lung disease or as a result of an isolated pulmonary vascular disease that may affect both the precapillary arterioles and the postcapillary venules, as well as a consequence of left heart involvement. These apparently different phenotypes often underlie a significant pathophysiologic overlap, which makes the diagnosis and management of these patients highly complex and uncertain.
Source: Heart Failure Clinics - Category: Cardiology Authors: Luna Gargani, Damien Voilliot, Michele D ’Alto, Gergely Agoston, Antonella Moreo, Walter Serra, Francesco Pieri, Fabio Mori, Karina Wierzbowska-Drabik, Marco Matucci-Cerinic, Alberto Moggi-Pignone Source Type: research
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