Genetic Polymorphism on the Pharmacokinetics and Pharmacodynamics of Platelet-derived Growth Factor Receptor (PDGFR) Kinase Inhibitors.

This article also provides an overview of: (1) general information on PDGFR kinase inhibitors; (2) pharmacokinetic parameters of PDGFR kinase inhibitors; (3) metabolic enzymes and transporters of PDGFR kinase inhibitors; (4) main drug interactions of PDGFR kinase inhibitors; (5) adverse events of PDGFR kinase inhibitors; and (6) genetic polymorphism on pharmacokinetics and pharmacodynamics of PDGFR kinase inhibitors. PMID: 29956623 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29956623?dopt=Abstract

Source: Current Drug Metabolism - June 28, 2018 Category: Drugs & Pharmacology Authors: Qian Y, Yu L, Zhang XH, Yuan-Zi QY, Zhao P, Sun LN, Wang YQ Tags: Curr Drug Metab Source Type: research