Interactions of vascular endothelial growth factor and p53 with miR-195 in thyroid carcinoma: possible therapeutic targets in aggressive thyroid cancers.

CONCLUSION: Our findings showed for the first time that miR-195 acts as a tumour suppressor and regulates cell cycle progression and apoptosis by targeting VEGF-A and p53 in thyroid carcinoma. The current study exhibited that miR-195 might represent a potential therapeutic target for patients with thyroid carcinomas having aggressive clinical behaviour. PMID: 29956628 [PubMed - as supplied by publisher]

https://www.ncbi.nlm.nih.gov/pubmed/29956628?dopt=Abstract

Source: Current Cancer Drug Targets - June 28, 2018 Category: Cancer & Oncology Authors: Maroof H, Irani S, Ariana A, Vider J, Gopalan V, Lam AK Tags: Curr Cancer Drug Targets Source Type: research