Formulation, pharmacokinetic evaluation and cytotoxicity of an enhanced-penetration paclitaxel nanosuspension.

CONCLUSION: To sum up, our results showed that the optimal formula could improve the solubility of PTX and the stability of the product. The PTX-Nanos developed in this research would be a promising delivery platform in cancer treatment.
PMID: 29956630 [PubMed - as supplied by publisher]

Source: Current Cancer Drug Targets - June 29, 2018 Category: Cancer & Oncology Authors: Cao Y, Wei Z, Li M, Wang H, Yin L, Chen D, Wang Y, Chen Y, Yuan Q, Pu X, Zong L, Duan S Tags: Curr Cancer Drug Targets Source Type: research