Th17 and IL-17 exhibit higher levels in osteonecrosis of the femoral head and have a positive correlation with severity of pain.

CONCLUSION: Th17 cells were recruited to an inflamed synovium, and inflammatory cytokine IL-17 was expressed at an increased level in the hip synovium of ONFH patients, which possibly contributed to clinical syndrome development. Overall, this study will help in identifying new therapeutic strategies for ONFH, especially the targeting of IL-17 to decrease inflammation and pain. < p > < /p >.
PMID: 29952419 [PubMed - in process]

Source: Endokrynologia Polska - June 30, 2018 Category: Endocrinology Authors: Zou D, Zhang K, Yang Y, Ren Y, Zhang L, Xiao X, Zhang H, Liu S, Li J Tags: Endokrynol Pol Source Type: research