Serum paraoxonase and arylesterase can be useful markers to predict neoadjuvant chemotherapy requirement in patients with breast cancer

Conclusion: BC patients have lower serum PON and ARE levels than healthy controls. Also, serum ARE levels (but not PON) were negatively correlated with body mass index in BC patients. Both serum PON and ARE levels were lower in patients who needed NAC than in patients who did not need such therapy.

Source: Journal of Cancer Research and Therapeutics - June 29, 2018 Category: Cancer & Oncology Authors: Yildiz Okuturlar Meral Gunaldi Hakan Kocoglu Mehmet Hursitoglu Asuman Gedikbasi Didem Acarer Ozlem Harmankaya Abdulbaki Kumbasar Source Type: research