Migraines in men linked to higher oestrogen levels

According to a study published in the journalNeurology, men who suffer from migraines have higher levels of oestrogen.Daily Mail
Source: Society for Endocrinology - Category: Endocrinology Source Type: news

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Caplacizumab-yhdp (Cablivi) is the first drug specifically indicated for acquired thrombotic thrombocytopenic purpura, a rare and potentially life-threatening blood clotting disorder. It is prescribed in combination with plasmapheresis and immunosuppressive therapy.The drug carries a warning that severe bleeding can occur with use, although the most common adverse effects are headache and minor bleeding from the nose or gums.Caplacizumab-yhdp is given initially as an iv bolus and then as a subcutaneous injection along with plasmapheresis.
Source: AJN - Category: Nursing Tags: Drug Watch Source Type: research
AbstractTo investigate the clinical manifestation, disease course, and prognosis of migraine patients with or without personality disorders. This cross-sectional study evaluated 61 patients with migraine diagnosed according to the criteria of the International Headache Society (IHS). Personality disorders were assessed with the Structured Clinical Interview for DSM-IV (SCID-II). Migraine severity was assessed with the Headache Impact Test-6 (HIT-6). We also used a structured clinical interview to diagnose comorbid mood disorders. Of the 61 patients, 20 (32.8%) had personality disorders. Personality disorders included obses...
Source: Acta Neurologica Belgica - Category: Neurology Source Type: research
People with obsessive-compulsive disorder (OCD) who don ’t achieve adequate relief from medication and cognitive-behavioral therapy may benefit from deep transcranial magnetic stimulation (dTMS), astudy inAJP in Advancesuggests.During dTMS treatment, a cap containing coils delivers magnetic pulses to stimulate nerve cells in the brain. The study compared active dTMS treatment with sham (inactive) treatment in 87 people with OCD, with participants in the active treatment group experiencing greater improvement in symptoms at the end of treatment and at a follow-up assessment four weeks later.The study, led by Lior Carm...
Source: Psychiatr News - Category: Psychiatry Tags: ajp in advance deep transcranial magnetic stimulation dTMS headache Lior Carmi obsessive-compulsive disorder OCD Yale-Brown Obsessive Compulsive Scale Source Type: research
A monthly injection of erenumab, the first new migraine drug for 20 years, was approved in Scotland in April. But in a blow to more than 500,000 people, NHS watchdog NICE rejected it in England.
Source: the Mail online | Health - Category: Consumer Health News Source Type: news
FRIDAY, May 24, 2019 -- Migraines in pregnant women are associated with an increased risk for pregnancy-associated hypertension disorders as well as an increased risk for a variety of adverse outcomes in the newborn, according to a study published...
Source: Drugs.com - Pharma News - Category: Pharmaceuticals Source Type: news
Condition:   Migraine Interventions:   Drug: Lasmiditan;   Drug: Placebo Sponsor:   Eli Lilly and Company Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Condition:   Episodic Migraine Interventions:   Drug: Galcanezumab;   Drug: Placebo Sponsor:   Eli Lilly and Company Not yet recruiting
Source: ClinicalTrials.gov - Category: Research Source Type: clinical trials
Authors: Kato Y, Hayashi T, Arai N, Tanahashi N, Takahashi K, Takao M Abstract Postural tachycardia syndrome (POTS) can cause orthostatic headache. However, it is difficult to differentiate POTS from spontaneous intracranial hypotension (SIH) caused by cerebrospinal fluid (CSF) leaks. We herein report a 53-year-old woman who presented with SIH associated with POTS. A cervicothoracic and lumbar epidural blood patch rapidly improved not only the headache but also the orthostatic tachycardia, suggesting POTS secondary to SIH. This case suggests that a CSF leak can cause secondary POTS. Therefore, POTS should be consid...
Source: Internal Medicine - Category: Internal Medicine Tags: Intern Med Source Type: research
The 'life-changing' injection has been approved for use in Scotland, but not yet in England.
Source: BBC News | Health | UK Edition - Category: Consumer Health News Source Type: news
This study investigates whether METH induces autophagy in the human dopaminergic neuroblastoma cell line SH-SY5Y, then examines the neuroprotective effects of gastrodin against autophagy in METH-treated SH-SY5Y cells. The effects of METH on the protein expressions of autophagy-related genes (LC3B and Beclin-1) were evaluated with and without gastrodin. The presence of autophagosomes in the METH-induced treatment with and without gastrodin is revealed through transmission electron microscopy. Pharmacological intervention was employed to study the role of the AKT/mTOR signaling pathway in the gastrodin-mediated neuroprotecti...
Source: Neuroscience Letters - Category: Neuroscience Source Type: research
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